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Cryosurgery is an effective medical treatment approach for treating solid cancerous malignancy, as it is a minimally invasive treatment therapy. The main aim of cryosurgery is to use extreme cold to destroy abnormal tissues while minimizing damage to healthy surrounding tissue. Recent technological advancements in cryogenics have attracted the attention of many researchers to study the low-temperature cryosurgical devices, generally termed cryoprobes. Saturated Liquid Nitrogen (LN2) from pressurized dewar is fed to the cryoprobe through a transfer hose. The fluid evaporates as it flows downstream because of various heat loads and experiences pressure drop. In this paper, a two-phase pressure drop solver is presented following a simplified one-dimensional analysis to estimate pressure losses occurring throughout the system. A qualitative discussion on the contribution of various pressure drop components is provided. It is observed that the major pressure loss occurs along the length of the cryoprobe tubes. The effect of the cryoprobe tube dimensions on the pressure drop is also studied. It is concluded that the miniaturized probe design demands higher system inlet pressure.

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