Neurotransmitters (NTs) are biologically active chemicals, which mediate the electrochemical transmission between neurons. NTs control numerous organic functions particularly crucial for life, including movement, emotional responses, and the physical ability to feel pleasure and pain. These molecules are synthesized from simple, very common precursors. Many types of NTs have both excitatory and inhibitory effects. Neurotransmitters’ imbalance can cause many diseases and disorders, such as Parkinson’s disease, depression, insomnia, increased anxiety, memory loss, etc. Natural food sources containing NTs and/or their precursors would be a potential option to help maintain the balance of NTs to prevent brain and psychiatric disorders. The level of NTs could be influenced, therefore, by targeting dietary habits and nutritional regimens. The progressive implementation of nutritional approaches in clinical practice has made it necessary to infer more about some of the nutritional NTs in neuropsychiatry. However, the importance of the intake of nutritional NTs requires further understanding, since there are no prior significant studies about their bioavailability, clinical significance, and effects on nerve cells. Interventional strategies supported by evidence should be encouraged.
Low back pain has become the most common critical health problem and it is well known for causing a personal, and community financial burden globally. Low back pain is demarcated as non-specific, non-radiating pain with no accompanying neurological signs and symptoms. Objective: The purpose of this study was to compare the effectiveness between Mckenzie exercises and back school exercises in the treatment of low back pain. Methods: This research included 36 patients who met the eligibility criteria. Prior to undertaking any examinations or receiving treatments, each participant in this study gave their ethical approval via filling out informed consent. Patients with nonspecific chronic back pain were divided randomly into 3 groups. In ‘group A’ only the conventional treatment was provided and in group 2 patients performed back school exercises. Similarly, in group 3 patients performed Mckenzie exercises. The lottery method was used to assign patients to these three randomized groups. All of these aforementioned groups received conventional therapy, which remained identical throughout the study. The conventional treatment included a hot pack for 10 minutes and back isometrics. Additionally, group A received conventional therapy, group B received conventional therapy along with back school exercises, and group 3 received Mckenzie exercises and conventional therapy. Each patient received treatment three times a week for of total 4 weeks. Roland Morris’s disability questionnaire was used to measure self-reported physical impairment due to low back pain. Moreover, a numeric pain rating scale was used to measure pain severity. Results: This study showed that patients receiving back school and Makenzie exercises showed marked improvement in pain and disability scores. Conclusion: This study concluded that Mckenzie exercises are more effective than back school exercises for the management of chronic nonspecific low back pain. That is because Mckenzie’s exercises not only decrease pain but equally improve, the flexibility and posture of the spine
Often impacting elderly women, the urinary incontinence is defined as the involuntary urine loss. Objective: The purpose of this study was to see the comparative effectiveness of pelvic floor muscle exercise with pilates training for treatment of urinary incontinence. Methods: The study's 36 patients who met the eligibility requirements were accepted. Prior to conducting any examinations, we obtained written informed consents from each participant. Patients with urinary incontinence were divided randomly into two groups. In ‘group A’ pelvic floor muscle exercises were applied while in ‘group B’ pilates training was applied. Allocation of patients in two groups was done by computerised generated list. Both groups received conventional therapy, which was the same throughout the study. The conventional therapy includes adductor strengthening of thigh and hot pack for 15 minutes. Group A received conventional therapy and pelvic floor muscle exercise while group B received conventional therapy and pilates training. Treatment frequency was 2 times a week. The duration of treatment was 6 weeks in both groups. Each patient's informed consent was obtained before the questionnaire was filled out. Scores were derived using the Questionnaire for Female Urinary Incontinence Diagnosis (QUID) and the International Consultation on Incontinence Questionnaire (ICIQ). Results: Patients in group A significantly outperformed those in group B. Conclusion: According to the study's findings, strengthening the pelvic floor muscles is superior than practicing pilates for treating stress urine incontinence. Pelvic floor exercises not only improved the urine leakage problem but also strengthened the muscle of abdomen and pelvis. So these exercises programs should be included in treatment plans along with medications in public health care for the welfare of patients.
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