Hematuria is defined as the presence of red blood cells in the urine and it may be observed microscopic or gross. Hematuria may originate from any site throughout the urinary tract, the glomerulus and interstitium or renal vasculature. Here, we present a 17-year-old boy who developed terminal hematuria after two months of treatment with isotretinoin for acne vulgaris. Radiological and cystoscopic assessment of the urinary system were normal. Isotretinoin treatment was stopped after dermatology consultation. In two weeks, terminal hematuria disappeared along with the dysuria, and the urine sample showed normal findings. Keywords: Acne vulgaris, adverse effect, gross hematuria, isotretinoin.
BACKGROUND To investigate the effects of the novel coronavirus disease 2019 (COVID-19) on spermatogenesis and the potential impact of COVID-19 on patients with normal semen parameters before the diagnosis of COVID-19. RESULTS The mean age of the patients was 31.82 ± 5.93 years. An abnormality was detected in at least one parameter in the semen analysis after COVID-19 in 9 patients (40.90%) whose semen analysis was normal before COVID-19. When post-COVID-19 sperm samples of the patients were divided into two groups as normal and abnormal, in the abnormal group, motility, progressive motility, and morphology were found to be significantly decreased, immotility significantly increased, and semen pH tended to be more alkaline. CONCLUSIONS Even though the effects of COVID-19 on spermatogenesis are not clearly understood, COVID-19 infection may have negative effects on semen parameters and play a role in fertilization. The expected duration for spermatogenesis to show normal findings may be longer in persons with post-COVID-19 infection.
Objective: The aim of this study is to report our experience on the management of seminal vesicle cyst which is an exceedingly rare acquired or congenital pathology. Materials and Methods: A retrospective chart review was conducted on seven patients diagnosed with seminal vesicle cyst between March 2011 to March 2020. Patients’ complaints, fertility, physical signs, diagnostic tests or intervention and the obtained findings, surgical intervention, duration of follow-up period, complications, recurrence and histologic examination of the cysts wall were evaluated in patients included. Results: Seven male patients, mean aged 36.29±13.45, IPSS 13.57±4.89, Qmax:21.77±3.42ml/s with seminal vesicle cysts were identified. The patients’ complaints included lower abdominal pain in one patient with giant seminal vesicle cyst and perineal pain, storage lower urinary tract symptoms in six patient. Five patients were fertile and spermiogram was within normal ranges, two patients were infertile. Six patients have ipsilateral renal agenesia. One asymptomatic patient and three patients with storage lower urinary tract sympmtoms followed without intervention. Two infertile patients were operated with transurethral resection. Seminal vesicle cyst >12 cm are evaluated as giant cysts and operated with open excision. Neither complications nor recurrences were observed. Histopathologic examination of the samples were reported to be compatible with seminal vesicle cyst. The median follow–up period was 96 months. Conclusion: The open surgical approach might be considered the definitive form of treatment for giant cysts. Although small asymptomatic seminal vesical cyst can be followed without intervention, the symptomatic cyst protruding to bladder can be managed by transurethral route.
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