Introduction and Objective: Worldwide, breast carcinoma is among the most common carcinoma in females. It is commonly seen site-specific carcinoma in females. Due to lack of education, breast carcinoma patients present in later stages of the disease to healthcare facilities, especially in developing nations. Patients with Locally advanced carcinoma breast (LABC) are commonly seen in developing nations and its treatment multidisciplinary approach. This study is our experience of clinical profile and LABC in a rural setup. Methodology: This is a retrospective and prospective study done in the medical college. Data was taken from 72 cases that were operated on at the institute from July 2018 to June 2021 and diagnosed with LABC. Patients who had histological evidence of malignancy were undergone surgery and other treatment modalities like neoadjuvant chemotherapy, adjuvant chemoradiation, and hormonal therapy. Results: Seventy-two patients diagnosed with LABC over three years were included in the study. The mean age was 51 years. The tumor size was more than 5cm in 60 (83.3%) patients. Involvement of axilla was present in 62 (86.1%) patients. All patients were diagnosed with histopathology after core needle biopsy. Neoadjuvant chemotherapy was given to 62 (86.1%) patients. Most of the patients (65) were undergone MRM as surgery, while the remainder (7) were undergone breast conservation therapy. Very few patients had postoperative complications, but with limited follow-up until this study, 5 (6.9%) patients had a recurrence of their study. Conclusion: In developing nations high percentage of Locally advanced breast carcinoma at presentation result in poor prognosis, high rate of metastasis, and mortality. Awareness and education about breast health and multimodality treatment of LABC will have long-term effects to decrease morbidity and mortality and improve outcomes.
Renal stone is a common condition affecting human beings of both genders and all age groups worldwide. Their presentation vary from unilateral loin region pain to nausea vomiting, to burning micturation or even haematuria. Patient profile of renal stone disease differs from one geographical region to another. Therefore this prospective observational study was conducted inDattaMeghe medical college, Wanadongri, Nagpur to find out patient characteristics of this region. 100 patients were included in the study. 82% patients were females most of whom were housewives. 48% patients belonged to the age group 41-60 years. Most common presentation was left sided flank pain. CT scan and USG abdomen were equally accurate in determining the size of the renal stone. Most of the females were managed conservatively whereas most males required intervention like URS or PCNL for their treatment.
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