This study focused on the development of a yogurt with an improved structure, texture and antioxidant activity level, by using apple pomace (AP) powder that was obtained in large quantities during the production of juices. The objective was to determine the sensory, physicochemical, textural and antioxidant characteristics of yogurt with the addition of AP powder (0.2–1.0%), during its shelf life. The physicochemical composition of AP was determined as follows: dietary fibers—62.73%, including pectin—23.12%; and the content of the antioxidant compounds in AP—total polyphenols (728.8 mg GAE/100 g DW), flavonoids (246.5 mg QE/100 g DW), tannins (63.54 mg TAE/100 g DW), carotenoids (4.93 mg/100 g DW) and the ability to inhibit the free radical (2433 µmol TE/100 g DW). AP addition reduces the yogurt fermentation time. The increase in the total dietary fiber content of up to 0.63% and in the insoluble fiber of up to 0.14% was attested in this study, as well as a significant increase in antioxidant activity, which correlated to the AP content. The addition of AP improved the textural properties of the yogurt during storage (20 days) and led to a significant reduction in syneresis. The influence of the AP content and the storage period on the textural characteristics and the overall acceptability of the yogurt samples were analyzed by the mutual information method. The AP content greatly influenced the yogurt’s quality, with the information analysis value for the overall acceptability being 0.965 bits. The analysis of the sensory and textural parameters of the yogurt during storage (1–20 days) demonstrated that samples with AP in proportions of 0.6–0.8% were evaluated with the highest score.
Abstract. Biological activity of the iridoid glycosides extract from Linaria genistifolia (L.) Mill. has been investigated, namely its infl uence on the resistance of the winter wheat Odesschi 51 plant to the caused by the Fusarium oxysporum and Helminthosporium avenae pathogenic fungi root rot. Our results indicate that summary iridoid glycosides from this plant, containing four major known compounds: 5-O-allosylantirrinoside, antirrinoside, linarioside and 6-β-hidroxiantirride, can be successfully employed in biological control of the afore-mentioned wheat pathogens: it stimulates wheat grains germination and embryonic root growth in conditions of fungal infection.
The aim of the research is to develop new bakery products with increased functional value by adding ingredients from the biomass of Spirulina platensis. High quality wheat flour (P1), oatmeal (P2) and whole wheat flour (P3) sticks were formulated with the addition of 3% S2 preparation based on spirulina, thus increasing the bioavailability of the active components in microalgae. It was established that the addition of S2 preparation in sticks results in an increase in the total polyphenol content by 41.67% in the P2 samples of oatmeal sticks and by 56.17% in the P3 samples of whole wheat flour. The addition of S2 leads to a decrease in the content of reducing sugars by up to 2.56% in P1, by 2.50% in P2 and by 2.19% in P3 compared to the control. In sticks with the addition of S2, the fat content of cyanobacterial origin increases by almost 3.2% in sample P1, by 4.4% in P2 and by 6.0% in P3 compared to the control samples. The research results show that the use of the preparation based on Spirulina platensis contributes to increasing the nutritional value of flour products through the increased intake of amino acids, fatty acids of cyanobacterial origin, minerals, vitamins and bioactive substances, which are missing in conventional products, consumed daily. The S2 preparation based on microalgae, rich in pigments - chlorophylls, carotenes and phycocyanins with beneficial properties for health, could be used as a natural food dyes.
The composition of the lipophilic and hydrophilic extracts from the Feteasca Neagra ground seeds, grown in three different vineyards, was studied. The physicochemical indicators of the seeds, the oil quality indicators and the total content of polyphenols and flavonoids in the extracts were determined. Some phenolic and flavanol constituents were identified and quantified using reversed-phase HPLC by gradient-elution. The Trolox equivalent antioxidant capacity assay proved the increased antioxidant activity of the hydrophilic extracts, with the highest DPPH• scavenging effect of almost 91.70 and 93.81%, an equivalent of 281.66 and 288.27 µM/L Trolox. It was concluded that the seeds recovered from Feteasca Neagra by-products are a rich source of functional compounds, with significant antioxidant properties.
2 Сибирский государственный медицинский университет (СибГМУ) Россия, 634050, г. Томск, Московский тракт, 2 3 Университет Томаша Бати в Злине Чешская Республика, 760 01, г. Злин, пр. Томаша Бати, 5678 4 Высшая школа химической технологии Чешская Республика, 166 28, г. Прага, пр. Технический, 5 РЕЗЮМЕ В настоящее время химиотерапия в сочетании с хирургией и лучевой терапией является наиболее ýффективным методом лечения рака. В то же время применение данного метода сопровождается серьезными побочными ýффектами, обусловленными неспецифичностью большинства химиотерапевтических агентов. В связи с ýтим разработка систем доставки лекарственных средств (СДЛС), способных обеспечить адресацию химиотерапевтического агента к раковым клеткам, а также его контролируемое высвобождение представляют собой перспективный подход для ýффективного лечения онкологических заболеваний.Цель работы -синтез нового СДЛС на основе поверхностно-модифицированных микрочастиц ноль-валентного железа, изучение его свойств в качестве носителя химиотерапевтического агента (ýффективность инкапсуляции, емкость загрузки, возможность контролируемого высвобождения химиотерапевтического агента) и безопасности.Материалы и методы. Частицы были получены методом восстановления хлорида железа (III) боргидридом натрия с последующей in situ модификацией поверхности 4-карбоксибензолдиазония тозилатом согласно модифицированной методике. Наличие функциональных групп на поверхности подтверждали методом ИК-спектроскопии с использованием спектрометра Nicolet iS5 Infrared Spectrometer (Thermo Scientific, США). Размеры и поверхностный заряд микрочастиц в растворе исследовали методом динамического рассеяния света и дзета-потенциала. Для оценки влияния pH окружающей среды на скорость высвобождения доксорубицина исследование проводили в моделированных физиологических условиях (pH 3,3; 5,5; 7,4). Изучение высвобождения под воздействием ультразвукового поля проводили одновременно при тех же условиях. Влияние модификации поверхности на ýффективность инкапсуляции оценивали при различных значениях рН (3,3; 5,5; 7,4) и концентрациях доксорубицина (0,2; 0,35; 0,5; 0,75; 1,0 мг/мл). Для подтверждения безопасности разработанной СДЛС определение цитотоксичности проводили на клеточной линии HeLa (ATCC® CCL-2™).Результаты. Предложена оригинальная методика получения носителя на основе микрочастиц нольвалентного железа с ковалентно присоединенным к поверхности хитозаном (Fe-CS), обладающе-* Власов Сергей Сергеевич,
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