The use of plasma as a passive antibody transfer source has more than 100 years of experience. Passive immunity is a technique to acquire immediate and transient protection by administering specif ic antibodies against the pathogen in question, through plasma obtained from convalescent or immunized individuals. In recent times, the use of convalescent plasma has been associated with the emergence of new pathogens such as those causing SARS, MERS, Ebola and COVID, as the lack of effective treatments or effective vaccines requires the use of old but potentially effective medical procedures.
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