In today's environment of shrinking reimbursement and coverage for many health care procedures, phototherapy for psoriasis has experienced a major decline. Once hailed as the cornerstone of psoriasis therapy, the increasing cost and demanding treatment regimen has resulted in low compliance, limiting access to this safe and effective mode of treatment. We have previously reported on the development and in vitro evaluation of a topical cream that selectively filters solar radiation to deliver narrow-band ultraviolet B. Here, we present the results of a pilot study in psoriasis patients. After an average of 38 sessions, all patients in the treatment arm responded to therapy. In particular, 43% of the treatment group experienced complete clearance and the remainder experienced at a minimum 50% lesion clearance. In contrast, none of the patients in the placebo arm experienced more than 20% lesion clearance. Our preliminary results demonstrate that the novel topical cream could provide a safe, effective, and convenient alternative to artificial light phototherapy.
Introduction: Acne vulgaris is a disorder of the pilosebaceous units. It is a chronic inflammatory dermatosis notable for open/closed comedones, papules, pustules, nodules. It is characterized by open comedones, closed comedones and pustular nodules. Aim of study: To examine factors underlying the quality of life of people with acne. Materials and method: A total of 576 respondents were included in the study. Acne specific Quality of Life questionnaire was used for this purpose. A prospective cross-sectional study was conducted, performed in private dermatological clinic as well as on-line. All analyses were conducted by using the SPSS.26 for Windows. Results and Discussion: 5.7 % were males and 94.3 percent were females. About 69.4% were aged between 15-25; 16.7 % between 26 to 30; 8.8% between 31 to 35 years old. Quality of life and emotional perception towards the social environment is demonstrated by the three components (self-perception of discomfort, functionality, and social factor). The reliability levels for the three components were .858 for self-perception of discomfort, .779 for functionality and .745 for the social factor. The factor analysis discovered three underlying factors: self-perception of discomfort, social factor and functionality in daily life. Conclusion: The findings confirm the general notion that people with acne have problems in quality of life and therefore special attention to psychological intervention should be given in the treatment of acne.
An important factor for successful implementation of accreditation is readiness of the healthcare organization for organizational changes. This study aims at assessing perceptions of the medical staff in healthcare organizations, regarding organizational changes related to accreditation, before starting the national accreditation in hospitals in R.Macedonia and to interconnect variables with the implementation of the process. A prospective cross-sectional study was conducted, performed in healthcare organizations throughout the R. Macedonia. Main tool for the study was a questionnaire consisting of seven questions of a closed type. Variables such as changes in line with law and regulations, introducing a new informational system, improving the working conditions, are perceived by the majority of the respondents as drivers toward successful implementation of the process. Conversely, high percent of the respondents find positive changes happen without introducing accreditation. Personnel is not certain who leads the changes and if resistance to change exists depending on not finding significance to answers yes, no, and the category without answer. For the majority of the respondents, accreditation is an effective tool for implementing changes that lead to quality in their organization.
Introduction: Acne vulgaris is a disorder of the pilosebaceous units. It is a chronic inflammatory dermatosis notable for open/closed comedones, papules, pustules, nodules. It is characterized by open comedones, closed comedones and pustular nodules. Aim of study: To examine factors underlying the quality of life of people with acne. Materials and method: A total of 576 respondents were included in the study. Acne specific Quality of Life questionnaire was used for this purpose. A prospective cross-sectional study was conducted, performed in private dermatological clinic as well as on-line. All analyses were conducted by using the SPSS.26 for Windows. Results and Discussion: 5.7 % were males and 94.3 percent were females. About 69.4% were aged between 15-25; 16.7 % between 26 to 30; 8.8% between 31 to 35 years old. Quality of life and emotional perception towards the social environment is demonstrated by the three components (self-perception of discomfort, functionality, and social factor). The reliability levels for the three components were .858 for self-perception of discomfort, .779 for functionality and .745 for the social factor. The factor analysis discovered three underlying factors: self-perception of discomfort, social factor and functionality in daily life. Conclusion: The findings confirm the general notion that people with acne have problems in quality of life and therefore special attention to psychological intervention should be given in the treatment of acne.
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