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Objective: This study proposes an algorithm for the detection of atrial fibrillation (AF), designed to operate on extended photoplethysmographic (PPG) signals recorded using a wrist-worn device of own design. Approach: Robustness against false alarms is achieved by means of signal quality assessment and different techniques for suppression of ectopic beats, bigeminy, and respiratory sinus arrhythmia. The decision logic is based on our previously proposed RR interval-based AF detector, but modified to account for differences between interbeat intervals in the ECG and the PPG. The detector is evaluated on simulated PPG signals as well as on clinical PPG signals recorded during cardiac rehabilitation after myocardial infarction. Main results: Analysis of the clinical signals showed that 1.5 false alarms were on average produced per day with a sensitivity of 72.0% and a specificity of 99.7% when 89.2% of the database was available for analysis, whereas as many as 15 when the RR interval-based AF detector, boosted by accelerometer information for signal quality assessment, was used. However, a sensitivity of 97.2% and a specificity of 99.6% were achieved when increasing the demands on signal quality so that 50% was available for analysis. Significance: The proposed detector offers promising performance and is particularly well-suited for implementation in low-power wearable devices, e.g. wrist-worn devices, with significance in mass screening applications.

Two expert cardiologists assessed the realism of simulated signals relative to real ECG signals, both in sinus rhythm and AF. The cardiologists identified the correct rhythm in all cases, and considered two-thirds of the simulated signals as realistic. The proposed model was also investigated by evaluating the performance of two AF detectors which explored either rhythm only or both rhythm and morphology. The results show that detection performance is strongly dependent on AF episode duration, and, consequently, demonstrate that the model can play a significant role in the investigation of detector properties.

This work introduces a method for detection of premature ventricular contractions (PVCs) in photoplethysmogram (PPG). The method relies on 6 features, characterising PPG pulse power, and peak-to-peak intervals. A sliding window approach is applied to extract the features, which are later normalized with respect to an estimated heart rate. Artificial neural network with either linear and non-linear outputs was investigated as a feature classifier. PhysioNet databases, namely, the MIMIC II and the MIMIC, were used for training and testing, respectively. After annotating the PPGs with respect to synchronously recorded electrocardiogram, two main types of PVCs were distinguished: with and without the observable PPG pulse. The obtained sensitivity and specificity values for both considered PVC types were 92.4/99.9% and 93.2/99.9%, respectively. The achieved high classification results form a basis for a reliable PVC detection using a less obtrusive approach than the electrocardiography-based detection methods.

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