Chronic cholesteatomatous otitis media is the particularly aggressive form of chronic otitis media.This ear infection can lead to functional impairment of the ear and exposes you to serious complications that can be life-threatening. The purpose of this work was to list the complications of cholesteatomatous otitis in our hospital center. Patients And Method: This is a descriptive retrospective study of cases of complicated cholesteatomatous otitis. The study was carried out within the university hospital center Andohatapenaka from January 2015 to December 2019 (5 years). Complications of chronic not cholesteatomatous otitis media have been ruled out. Results: The frequency of cholesteatomatous otitis media is 2.57%. It mainly affects patients between 10 and 20 years old with a male predominance. Extra-cranial complications are more frequent (78.94%) compared to intracranial complications. The circumstances of discovery are dominated by otorrhea (31.57%) and retro-auricular swelling (21.05%). The clinical signs are variable and depend on the complications. The otological history badly or not treated (60.52%) remains a predictive factor of these complications. Computed tomography has a very important place in the diagnostic component. Conclusion : Cholesteatomatous otitis media is always at risk of serious complications in the absence of well-adapted treatments.Complications can be functional which blames the hearing or vital following the endocranial extension
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