Globally, breast cancer is the most diagnosed neoplasm in women. In some countries, it's consolidated as the type of neoplasm that causes the most deaths, being responsible for premature deaths. The molecular classification of cancer allows specific treatment for each patient; however, some types have resistance that results in an unfavorable prognosis. For this reason, researches are being developed in order to use the complexity of the immune system as a tool to combat the heterogeneity of breast cancer. Lately, studies have evaluated the leukocyte infiltrates present in the tumor microenvironment have become a promising field in therapeutic innovation, which is based on the cellular composition of the neoplastic environment of cancers with poor prognosis, whose immunotherapeutic action is specific to each molecular subtype. The expression of immune cells in the tumor microenvironment has potential for oncological parameters that can help in the treatment and also to define the prognosis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.