Basal cell carcinoma (BCC) is considered to be the most common cancer in humans. It has a slow growth rhythm, and for this reason, metastases are rare. For our retrospective study, we selected 180 patients from those who underwent surgery for a variety of skin tumours between January 2019 and August 2022 and whose histopathological examination revealed basal cell carcinoma. All surgeries were performed by plastic surgeons at the “St. John” hospital in Bucharest. The aim of this article is to provide observational data regarding BCC—in terms of histopathology and diagnostic and therapeutic management and to integrate these data into the current knowledge of this pathology.
Objectives:The aim of this study is to introduce an automatic algorithm that identifies abdominal aorta and estimates its diameter and aorta intima media thickness (aIMT) from videos recorded during routine third trimester ultrasonographic fetal biometry Methods: aIMT was measured in singleton pregnant women during routine third trimester ultrasonography. In each frame, the algorithm locates and segments the region corresponding to aorta by means of an active contour driven by two different external forces: a static vector field convolution force and a dynamic pressure force. Then, in each frame, the mean diameter of the vessel is computed, to reconstruct the cardiac cycle: in fact, we expect the diameter to have a sinusoidal trend, according to the heart rate. From the obtained sinusoid, we identified the frames corresponding to the end diastole and to the end systole. Finally, in these frames was assessed the aIMT. The correlation between end-diastole and end-systole aIMT automatic and manual measures is 0.90 and 0.84 respectively. Results: The mean aorta diameter (blue line) and the mean aIMT (red line) estimated in 78 subsequent frames are shown: for visual purpose the values of aIMT are scaled to be superimposed to aorta diameter. The videos were acquired with a frame rate of 25 frames per second, thus three seconds of acquisition are shown. The estimated heart rate in coherent with physiological fetal heart rate. The correlation between end-diastole and end-systole aIMT automatic and manual measures was 0.90 and 0.84 respectively.
Conclusions:The high values of correlation between manual and automatic results suggest that the proposed algorithm provides a reliable technique to faster the measure of important structures during ultrasonographic fetal biometry, such as aorta diameter and aIMT. Besides, being fully automatic, it allows avoiding the problems of intra-and inter-operator variability, typical of any manually performed measure.
P17: FETAL NEUROSONOGRAPHY AND CNS ANOMALIES CASE REPORTS
P17.01 Fetal epidural hematoma following ''non primary'' Cytomegalovirus infection: a case report
Fetal Medicine Unit, Department of Obstetrics, St George's Hospital, London, United KingdomHuman Cytomegalovirus (CMV) is a common cause of intrauterine infection, and occurs in 0.2-2.2% of all live births in western countries. A 30 years old pregnant woman gravida 1 at 20 weeks of gestation was referred because of suspected fetal hydrocephalus at screening second trimester ultrasound scan. A detailed scan revealed an intracranial hyper-echoic space-occupying lesion overlying the left temporo-parietal lobes. The anterior horns of the ventricles appeared prominent, although the transverse size of the right lateral atria was within normal range (9.28 mm) with mild midline shift. Cavum septum pellucidi and third ventricle were compressed. The fourth ventricle appeared dilated. Hyper-echoic bowel was revealed at ultrasound scan. Fetal MRI was performed and sequences were acquired confirming the US suspect of epidural hemorrha...
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