Titanium alloys are widely used in medical applications, due to their good mechanical properties, high corrosion resistance and biocompatibility. The aim of this paper was to investigate the cytotoxicity of novel titanium alloys: Ti21Nb6Zr15Ta, Ti25Nb10Zr8Ta, Ti17Nb5Zr5Al, Ti7Nb7Zr2Al with fibroblast-like cells derived from human osteosarcoma cell line (HOS). The results were compared with that of conventional biomedical alloys, like Ti6Al7Nb and Ti6Al4V. In vitro citotoxicity of titanium alloys was evaluated by fluorescence microscopy and MTT colorimetric assay. The results showed that the materials analyzed had no cytotoxic effects on HOS fibroblast-like cells, permitting their attachment and proliferation. Also the new titanium alloys present a higher cell viability than that of the conventional alloys. As a consequence, the TiNbZrTa and TiNbZrAl alloys can be considered as potential candidates for biomedical applications.
The corrosion behavior of two TiNbTaZr alloys (Ti25Nb8Ta10Zr and Ti21Nb15Ta6Zr) in Dulbecco's minimum essential medium (MEM) are evaluated and its protective ability is compared with that of Cp‐Ti, to ascertain their stability for biomedical application. All the samples were examined using electrochemical techniques: electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization curves. The electrochemical corrosion parameters obtained from the EIS and potentiodynamic polarization curves indicated a typical passive behavior for TiNbTaZr alloys. In addition, scanning electron microscopy was employed to observe the surface morphology after polarization test in MEM solution. Low anodic current density values were obtained from the polarization curves, indicating a typical passive behavior for TiNbTaZr alloys. EIS studies showed high impedance values for all samples, increasing with exposure time. The Ti21Nb15Ta6Zr alloy appears to possess superior corrosion resistance than the Ti25Nb8Ta10Zr alloy and Cp‐Ti in MEM solution.
Ti-Nb-Zr-Ta alloys represent a new generation of biomaterials with possible applications in the orthopedic field, being developed in order to eliminate the negative aspects of the current orthopedic biomaterials, which consist mainly in a low biocompatibility with human tissues and high values of modulus of elasticity compared to the human bone. This paper presents a comparative study of new titanium alloys, corresponding to the Ti-Nb-Zr-Ta system: Ti-21Nb-6Zr-15Ta and Ti-25Nb-10Zr-8Ta, which were analyzed by scanning electron microscopy, X-ray diffraction and microindentation. The both alloys are classified as near-β alloys. The addition of alloying elements such as Ta, Nb and Zr represents a good solution for lowering modulus of elasticity, which is an important factor for reducing bone resorption and therefore for preventing implant failure.
Titanium alloys corresponding to Ti-Nb-Zr-Ta system represent a new generation of biomaterials, which were developed for medical applications like metal-ceramic. They are composed of non-toxic and non-allergenic elements and have lower values of modulus of elasticity compared to that of the current biomaterials used in dentistry or orthopedics. In this paper are presented two new titanium alloys (Ti-21Nb-6Zr-15Ta and Ti-25Nb-10Zr-8Ta), which were characterized from structural aspect, mechanical and surface properties point of view using scanning electron microscopy, X-ray diffraction, wear properties, Vickers microhardness measurement. Also, was tested the cytotoxicity of these alloys using direct contact method. The results showed that the investigated alloys have a biphasic structure composed of β-solid solution with intragranular lamellar structures specific to α”. The experimental results shown that new titanium alloys from the system Ti-Nb-Zr-Ta present much better properties compared to that of the metallic biomaterials used currently.
This paper studies the way how a sample with a 40Cr130 coating behaves to contact fatigue wear from the perspective of plastic deformations. The sample is made of an 18MnCr11 alloy steel. The coating was deposited in electric arc using the Smart Arc 350 installation from Sulzer Metco. The samples was subjected to fatigue wear on the AMSLER installation in limit and mixed lubrication conditions. The samples were subjected to wear for 30 hours, at a loading force of 177 N. The moving sample had a rotational speed of 375 rot/min. Different combinations of contact materials were used for the test samples: coating coating and coating base material. The results were highlighted using the QUANTA 200 3D DUAL BEAM electron microscope.
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