Facial motion plays a fundamental role in the recognition of facial expressions in primates, but the neural substrates underlying this special type of biological motion are not well understood. Here, we used fMRI to investigate the extent to which the specialization for facial motion is represented in the visual system and compared the neural mechanisms for the processing of non-rigid facial motion in macaque monkeys and humans. We defined the areas specialized for facial motion as those significantly more activated when subjects perceived the motion caused by dynamic faces (dynamic faces > static faces) than when they perceived the motion caused by dynamic non-face objects (dynamic objects > static objects). We found that, in monkeys, significant activations evoked by facial motion were in the fundus of anterior superior temporal sulcus (STS), which overlapped the anterior fundus face patch. In humans, facial motion activated three separate foci in the right STS: posterior, middle, and anterior STS, with the anterior STS location showing the most selectivity for facial motion compared with other facial motion areas. In both monkeys and humans, facial motion shows a gradient preference as one progresses anteriorly along the STS. Taken together, our results indicate that monkeys and humans share similar neural substrates within the anterior temporal lobe specialized for the processing of non-rigid facial motion.

In this research, we use a modeling framework developed for oil and gas evaluation in the western United States to determine the modeled impacts of emissions associated with oil and gas production on air pollution metrics. We show that oil and gas production may have a significant negative impact on air quality and ecosystem health in some national parks and other Class I areas in the western United States. Our findings are of particular interest to federal land managers as well as regulators in states heavy in oil and gas production as they consider control strategies to reduce the impact of development.

Purpose of reviewRecognition of skin findings associated with tumor predisposition syndromes can prompt early evaluation and surveillance and improve management. Additionally, knowing when to test and when to defer performing genetic testing can streamline management. This article reviews tumor predisposition syndromes with recently characterized skin findings and disorders for which early recognition and counseling can impact the course of disease.Recent findingsCafé au lait macules (CALMs) are important in many tumor predisposition syndromes, and ‘atypical’ CALMs are associated with constitutional mismatch repair deficiency and Fanconi anemia. Melanoma predisposition syndromes caused by pathogenic variants in POT1 and BAP1 are more recently described, and both are associated with Spitzoid tumors. Somatic pathogenic variants can cause segmental nevoid basal cell carcinoma syndrome and a mosaic form of Peutz–Jeghers syndrome. Patients with PTEN hamartoma syndrome have increased risk for melanoma but this might not occur until adulthood.SummaryThe cutaneous manifestations of tumor predisposition syndromes can aid diagnosis. Early photoprotection is key to modifying a main risk factor for skin cancer in many of these syndromes. Implementing surveillance guidelines facilitates early detection of tumors.

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