Wellness assessment refers to the evaluation of physical, mental, and social well-being. This work explores the possibility of applying technological tools to assist clinicians and professionals to improve the quality of life of people through continuous monitoring of their wellness. The contribution of this paper is manifold: a coarse-grained localization system is responsible for monitoring and collecting data related to patients, while a novel wellness assessment methodology is proposed to extract quantitative indicators related to the well-being of patients from the collected data. The proposed system has been installed at “Il Paese Ritrovato", an innovative health-care facility for Alzheimer’s in Monza, Italy; first satisfactory results have been obtained, and the dataset shows great potential for several applications.
We have simplified the published procedure (5) for measuring sweat rates in individual human sweat glands. Sweat secretion rates were obtained from sweat drops secreted on the forearm by multiple individual glands. We computed a ratio between CFTR-dependent (by intradermal microinjection of a β adrenergic cocktail) and CFTR-independent (by methacoline as cholinergic stimulus) sweat secretion rates. We obtained a reproducible, approximately linear readout of CFTR function with measurements performed by two different independent teams. We considered three groups (CF subjects, CF carriers and non-CF controls, n=22 in each group); their mean ratios was respectively 0.000, 0.104 and 0.205 The average ratio of CF subjects was consistent with diagnosis in 3 additional cases clinically resembling CF. All groups were clearly discriminated, with sensibility and specificity ranging from 82% to 100%. A software was developed for detecting sweat droplets. This bioassay is suitabile for multicentre studies focusing on CFTR targeted therapies, controversial diagnosis and functional relevance of rare CFTR mutations.
The most frequent form of dementia is Alzheimer’s Disease (AD), a severe progressive neurological pathology in which the main cognitive functions of an individual are compromised. Recent studies have found that loneliness and living in isolation are likely to cause an acceleration in the cognitive decline associated with AD. Therefore, understanding social behaviours of AD patients is crucial to promote sociability, thus delaying cognitive decline, preserving independence, and providing a good quality of life. In this work, we analyze the localization data of AD patients living in assisted care homes to gather insights about the social dynamics among them. We use localization data collected by a system based on iBeacon technology comprising two components: a network of antennas scattered throughout the facility and a Bluetooth bracelet worn by the patients. We redefine the Relational Index to capture wandering and casual encounters, these being common phenomena among AD patients, and use the notions of Relational and Popularity Indexes to model, visualize and understand the social behaviour of AD patients. We leverage the data analyses to build predictive tools and applications to enhance social activities scheduling and sociability monitoring and promotion, with the ultimate aim of providing patients with a better quality of life. Predictions and visualizations act as a support for caregivers in activity planning to maximize treatment effects and, hence, slow down the progression of Alzheimer’s disease. We present the Community Behaviour Prediction Table (CBPT), a tool to visualize the estimated values of sociability among patients and popularity of places within a facility. Finally, we show the potential of the system by analyzing the Coronavirus Disease 2019 (COVID-19) lockdown time-frame between February and June 2020 in a specific facility. Through the use of the indexes, we evaluate the effects of the pandemic on the behaviour of the residents, observing no particular impact on sociability even though social distancing was put in place.
Low Resolution Thermal Array Sensors are widely used in several applications in indoor environments. In particular, one of these cheap, small and unobtrusive sensors provides a low-resolution thermal image of the environment and, unlike cameras; it is capable to detect human heat emission even in dark rooms. The obtained thermal data can be used to monitor older seniors while they are performing daily activities at home, to detect critical situations such as falls. Most of the studies in activity recognition using Thermal Array Sensors require human detection techniques to recognize humans passing in the sensor field of view. This paper aims to improve the accuracy of the algorithms used so far by considering the temperature environment variation. This method leverages an adaptive background estimation and a noise removal technique based on Kalman Filter. In order to properly validate the system, a novel installation of a single sensor has been implemented in a smart environment: the obtained results show an improvement in human detection accuracy with respect to the state of the art, especially in case of disturbed environments.
This paper aims at understanding the social behavior of people with dementia through the use of technology, specifically by analyzing localization data of patients of an Alzheimer’s assisted care home in Italy. The analysis will allow to promote social relations by enhancing the facility’s spaces and activities, with the ultimate objective of improving residents’ quality of life. To assess social wellness and evaluate the effectiveness of the village areas and activities, this work introduces measures of sociability for both residents and places. Our data analysis is based on classical statistical methods and innovative machine learning techniques. First, we analyze the correlation between relational indicators and factors such as the outdoor temperature and the patients’ movements inside the facility. Then, we use statistical and accessibility analyses to determine the spaces residents appreciate the most and those in need of enhancements. We observe that patients’ sociability is strongly related to the considered factors. From our analysis, outdoor areas result less frequented and need spatial redesign to promote accessibility and attendance among patients. The data awareness obtained from our analysis will also be of great help to caregivers, doctors, and psychologists to enhance assisted care home social activities, adjust patient-specific treatments, and deepen the comprehension of the disease.
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