A record-linkage study was carried out between the Italian AIDS Registry and 24 Italian cancer registries to compare cancer excess among persons with HIV/AIDS (PWHA) before and after the introduction of highly active antiretroviral therapy (HAART) in 1996. Standardised incidence ratios (SIR) were computed in 21951 AIDS cases aged 16 -69 years reported between 1986 and 2005. Of 101 669 person-years available, 45 026 were after 1996. SIR for Kaposi sarcoma (KS) and non-Hodgkin lymphoma greatly decreased in 1997 -2004 compared with 1986 -1996, but high SIRs for KS persisted in the increasingly large fraction of PWHA who had an interval of o1 year between first HIV-positive test and AIDS diagnosis. A significant excess of liver cancer (SIR ¼ 6.4) emerged in 1997 -2004, whereas the SIRs for cancer of the cervix (41.5), anus (44.0), lung (4.1), brain (3.2), skin (non-melanoma, 1.8), Hodgkin lymphoma (20.7), myeloma (3.9), and non-AIDS-defining cancers (2.2) were similarly elevated in the two periods. The excess of some potentially preventable cancers in PWHA suggests that HAART use must be accompanied by cancer-prevention strategies, notably antismoking and cervical cancer screening programmes. Improvements in the timely identification of HIV-positive individuals are also a priority in Italy to avoid the adverse consequences of delayed HAART use.
Gold catalysts supported on iron oxide have been characterized by X-ray photoelectron spectroscopy (XPS). Depending on the method of preparation and pretreatment, di †erent gold species have been detected on the catalyst surface. In the absence of thermal treatment, the XPS spectra of the impregnated samples show the formation of gold(III) (oxy)chloride species. No metallic gold is formed. Both metallic and oxidized gold species are instead present on the surface of the samples prepared by coprecipitation. Oxidized gold(III) species are predominant on the uncalcinated catalysts. After treatment at high temperature and/or under reaction conditions the amount of metallic gold increases. The XPS data have been correlated with the activity of the investigated catalysts in the oxidation of carbon monoxide at low temperature.
Lo studio è stato condotto in collaborazione con medici, epidemiologi e ricercatori in tutta Italia che sono entrati a far parte del Cancer and AIDS Registries Linkage Study. Tale stuudio ha prodotto una pubblicazione a stampa in cui compare tra gli autori la dr Rosa Maria Limina, di questa Università, che ha inserito questo prodotto con il codice 31053 nella tipologia Articolo su Rivista
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