Antimony compounds are the cornerstone treatments for tegumentary leishmaniasis. The
reactivation of herpes virus is a side effect described in few reports. We conducted
an observational study to describe the incidence of herpes zoster reactivation during
treatment with antimony compounds. The global incidence of herpes zoster is
approximately 2.5 cases per 1,000 persons per month (or 30 cases per 1,000 persons
per year). The estimated incidence of herpes zoster in patients undergoing antimony
therapy is higher than previously reported.
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