Both findings call for an international public health and drug agencies surveillance of 'real-world' antipsychotic medication to ensure the optimal choices in treatment guidelines for SZ.

Two groups of adult subjects were exposed to central and/or peripheral visual motion affecting either the foreground or the background of the visual field. Body sway and duration of vection over a 1-minute period were measured. The results showed that depth periphery and retinal periphery both play a role in the regulation of posture and in vection. Movement limited to the foreground produced little vection or postural sway compared with motion located in the background. The results also show that motion covering the periphery of the visual field is more efficient in inducing vection and body sway than motion restricted to the centre of the visual field.

It has been demonstrated many times that the posture of infants is affected by movement of the visual environment. However, in previous studies, measurements taken with infants less than 10 to 12 months of age have always been recorded with the infants in a sitting position. An experiment is reported in which the postural reactions to a sinusoidal movement of the visual environment were recorded in infants 7 months of age and older standing with support. Fifty subjects divided into five groups (mean age 7.15 to 48.6 months) participated in the experiment. The groups differed in age and motor ability. Movement of the visual environment was achieved by means of a floorless room that could be moved sinusoidally in the anteroposterior axis. The subjects had to stand holding a horizontal bar fixed to a force-measurement platform. For each subject, measurements were made during four 60 s intervals: two with movement of the room and two with the room stationary. For all groups, reactions in the anteroposterior axis were stronger than in the lateral axis and this was true for both stimulus conditions. Comparison of the differences between the movement and stationary conditions in the anteroposterior axis, as a function of age, shows that the youngest infants seemed paradoxically to give stronger reactions when the room was stationary than when it was moving; the inverse was true for older infants and this difference increased with age. An analysis of the data with fast Fourier transforms reveals that the majority of subjects showed a pattern of postural reactions where the dominant (peak) frequency was identical to the peak frequency of room movement.(ABSTRACT TRUNCATED AT 250 WORDS)

Aesthetic preferences for overlapping geometrical figures were studied with reference to perceptual abilities and age of 80 subjects in the context of the theory of functional pleasure. According to the working hypothesis, the level of complexity (number of crossings) of the preferred stimulus varies with the subjects' perceptual capacities as measured by an overlapping figures test and an embedded figures test. The results confirm this hypothesis with significant correlations between the two variables. Changes in preference for complexity with age (20 subjects each of 6, 8, 11, and 14 yr.) is seen as related to changes in perceptual ability. The general interpretation suggests that aesthetic preferences are partly based on the pleasure resulting from the quality of functioning of the perceptual mechanisms.

The ADAPTE methodology provided structure, rigour and efficiency to the trans-contextual adaptation of guideline recommendations. We will share the challenges associated with the adaptation of clinical recommendations and organizational strategies for a mental health guideline, and the dissemination of the practice protocol in primary care.