Background: We report the case of a 64-year-old woman with bilateral manifestation of Meige syndrome (MS) successfully treated with left-side unilateral ventroposterolateral pallidotomy. Methods: Symptoms were evaluated according to the Burke-Fahn-Marsden dystonia rating scale. Head tremor, blepharospasm and orofacial dyskinesia were measured with an infrared, video-based, computerized, real-time passive marker-based analyzer of motions (RTPAM). Results: The Burke-Fahn-Marsden score showed a 90.2% reduction (from 25.5 to 2.5) at 6 months, and an 88.2% long-lasting benefit (to 3.0) at the 3-year follow-up with good bilateral control of the blepharospasm and orofacial movements. The RTPAM showed a substantial regression of acceleration for all markers, and abolishment of the 4.8-Hz head tremor. The correlation between symmetrical markers, and between markers within the right and left sides, was significantly decreased. Conclusions: Pallidotomy with staged procedure is recommended for the treatment of MS in patients on whom deep brain stimulation could not be performed. In case of good bilateral benefits from the unilateral procedure, contralateral surgery is not needed. The RTPAM is a useful tool for the mapping of facial involuntary movements.
Considering the anamnestic data, it could be useful to perform DC at 20-22 mmHg ICP in young patients in order to prevent the potential of very fast brain swelling if there is no possibility to perform durotomy within 20 min after the onset of raising the ICP. It is especially considerable in poor countries where the emergency route could be less organized because of locations of building and extreme load of the staff. Further controlled trials are necessary to evaluate the indication and standardization of early decompressive craniectomy as a standard preventive therapy in pediatric severe traumatic brain swelling.
Decompressive craniectomy with durotomy, is possible as a last resort therapy for severe traumatic brain swelling. Although the method successfully diminishes the ICP, partial or total vascular insufficiency occurs in the herniated part of the brain. The actual cause of the insufficiency is most likely due to the compression of the cortical veins and arteries supplying the herniated brain, caused by shearing and pressure forces between the dural edge and brain tissue. Furthermore venous congestion may induce edema in the protruding parts of the brain, thus further compromising neurone viability. The new surgical technique consists of a stellate type durotomy and the creation of a vascular tunnel around the main cortical veins and arteries, with the aim that the vessels do not become compressed by the dural or bone edge. The effect of the novel vascular tunnel technique was proven by measuring the blood flow of the protected and nonprotected veins with Doppler UH, intra-operatively. In the last two years 28 patients were operated on with this method. One case of edema was caused by SAH. All were in severe GCS 3 or GCS 4 status, with more than 30 mmHg ICP. In comparison with the traditional surgical and nonsurgical treatment, where the reported mortality rates are 80%-90% in these severe cases the mortality rate was reduced to 40%, and recovery (GOS 4, 5) rate also increased significantly. With this technique the ICP was significantly reduced and further edema and vascular insufficiency was prevented. This was due to protection of the arterial circulation and venous drainage of the herniated part of the brain, by the formation of a vascular tunnel at the durotomy edges.
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