In this paper, we summarize three ligand design studies performed
using the program SMoG, which was
developed in our lab. The aim of this presentation is to
communicate through examples the potential of this
method:
the richness of the molecules that can be developed and the ease with
which they are found. In particular, we
present suggestions for ligands to Src SH3 domain (specificity pocket
and LP site) and CD4.
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