An experimental model of chronic oral candidiasis, which adequately reproduces the recurrence of the disease and can be used to study the major pathogenic mechanisms of the disease and determine the effectiveness of antifungal drugs. Under the experimental conditions studied pathological changes that occur at different stages of infection in the mouth, the digestive system, liver, and spleen of experimental animals. The dynamics of the immune response during relapse of experimental oral candidiasis and stages of secondary imunodefficiency postinfection.
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