The authors of the article set a goal to identify the most accurate and economical methods for assessing the innovative potential of megacity in terms of the used resources. For that purpose, methods were selected, calculations were carried out for two of them, which were suitable for the goal and described in detail in the methodological literature. The results of two other methods presented in the public domain for comparable periods of time for three selected regions were used. The study used materials from Russian and foreign sources. Based on the results of the work done, certain conclusions were made that allow a more accurate selection of methods for assessing the innovative potential of cities, considering the objectives of such an assessment, as well as the resource availability of a group of researchers. A critical view is also presented on the further application of all methods, which requires researchers of the local innovation potential to have the accuracy, objectivity in assessments, and independence in their interpretation.
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