Epithelioid hemangioendothelioma (EHE) is one of the rarest vascular tumor found in the brain. In the pediatric group of patients, the proportion of EHE is only 0.02% of all brain neoplasms, and therefore oncogenesis and the causes are currently not well understood. Intracranial localization of EHE is extremely rare, nevertheless, this type of neoplasm should be included in the differential diagnostic series when multiple small intracerebral masses with hypointense MR signal in T2 mode are detected on magnetic resonance imaging. No specific therapy is currently developed for this disease, the optimal treatment is surgical removal of the volumetric mass if this type of treatment is possible. This article presents a clinical case of a primary multiple CNS lesion in a 14-year-old child with a long history of epilepsy. According to our data, the presented clinical case is the only one registered in the world, with primary multiple CNS EHE of the brain in the pediatric population
Despite the low prevalence of cerebrovascular diseases in childhood, up to 60% of children realize acute symptomatic epileptic seizures and up to 30% of patients develop post-stroke epilepsy in the long-term period. The lack of a unified terminology and temporal criteria for both acute symptomatic epileptic seizures and post-stroke epilepsy complicates the analysis of the studied groups. Many studies are limited to small groups, proprietary terminology, different age medians, and inclusion criteria. Both clinical and instrumental risk factors for the development of post-stroke epilepsy in childhood have not been identified, which makes it difficult to identify risk groups and predict the outcome in the long term period. The only significant risk factor in most publications is «younger age», but its boundaries are blurred. Most studies are retrospective, which may affect the incidence and type of epileptic seizures in acute cerebrovascular accident. Electroencephalography is the most informative method for detecting subclinical changes and identifying risk groups. Continuous electroencephalography is effective primarily in the detection of non-convulsive status epilepticus. Currently, there are no unified protocols for examining stroke patients, both at the onset and in follow-up. The search for articles was carried out in the scientific platforms PubMed, Google Scholar, eLIBRARY.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.