Depression deter mental catabolic effect over the time, symptomatically affects quality of life which leads to worse health outcomes that linked to higher mortality and morbidity rates with huge impact on public health. Chronic conditions like Cardio Vascular Diseases (CVDs) deteriorates patient health with cognitive impairment that progresses to somatic dysfunction, which can exacerbate to the occurrence and development of depression with the increased risk of inducing Chronic Diseases. Depression are often neglected, overlooked and remains unrecognized and undertreated in the patient, especially in CVDs patient are considered as normal that instances to poor prognosis. The association of depression and CVDs are not incidental, but the lack of diagnosis for the coexistence of these co-morbid condition and poor treatment hindrance the disease outcome. Depression emerges an alarming cardio vascular risk factor which is associated with higher cost of care for the patient as well as burden to the healthcare system. Prior detection and identification with rational intervention of depression at CVDs will help to change the scenario by improving the standard of health and overall quality of life of patient. Here, in this study we assess the prevalence of depression at cardio vascular disease patient in Nilgiris population.
Antibiotics resistance is an emerging problem in the management for infectious diseases. Patients are many a time prescribed with antibiotics without knowing that particular antibiotic sensitivity pattern with respect to the infectious microorganism. This study aims to detect the type of microbes causing certain infections in the hospital and also to detect the sensitivity pattern of the antibiotics to these microbes. We conducted a prospective study for six months on the neonates who were admitted in NICU. The blood samples were collected from these neonates before the administration of antibiotics. The swab samples were also collected from various places of this hospital to detect the types of microorganisms present in the hospital and to study the sensitivity of the antibiotics toward these microbes. The antibiotics used in this study were Gentamicin, Ampicillin, Cefotaxime, Amikacin, Piperacillin, Meropenam, and Vancomycin. Staphylococcus aureus and Streptococcus pneumoniae were found to be the most common pathogens implicated in neonate's infection. All the organisms showed absolute sensitivity mostly to Ampicillin, Gentamicin, and Piperacillin and resistant to Cefotaxime, Amikacin, and Vancomycin. Staphylococcus aureus, Streptococcus pneumoniae, Hemophilus infleunzae, Kleibseilla pneumoniae, Escherichia coli were the most common microorganism found in the swab samples collected from the hospital. Most of these microorganisms shows sensitivity towards Ampicillin, Gentamicin, and Meropenam but were resistance to Cefotaxime, Amikacin, and Vancomycin. A routine bacterial surveillance of prevalent organisms and the study of the sensitivity patterns of the pathogens responsible for neonatal infection should be made an essential component for neonatal care. This information from many parts of the country will be important in policymaking on antimicrobial use not only locally but also internationally.
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