Diabetic maculopathy is one of the retinal abnormalities in which a diabetic patient suffers from severe vision loss due to the affected macula. It affects the central vision of the person and causes blindness in severe cases. In this article, we propose an automated medical system for the grading of diabetic maculopathy that will assist the ophthalmologists in early detection of the disease. The proposed system extracts the macula from digital retinal image using the vascular structure and optic disc location. It creates a binary map for possible exudate regions using filter banks and formulates a detailed feature vector for all regions. The system uses a Gaussian Mixture Model-based classifier to the retinal image in different stages of maculopathy by using the macula coordinates and exudate feature set. The evaluation of proposed system is performed by using publicly available standard retinal image databases. The results of our system have been compared with other methods in the literature in terms of sensitivity, specificity, positive predictive value and accuracy. Our system gives higher values as compared to others on the same databases which makes it suitable for an automated medical system for grading of diabetic maculopathy.
Glaucoma is a chronic and irreversible neuro-degenerative disease in which the neuro-retinal nerve that connects the eye to the brain (optic nerve) is progressively damaged and patients suffer from vision loss and blindness. The timely detection and treatment of glaucoma is very crucial to save patient's vision. Computer aided diagnostic systems are used for automated detection of glaucoma that calculate cup to disc ratio from colored retinal images. In this article, we present a novel method for early and accurate detection of glaucoma. The proposed system consists of preprocessing, optic disc segmentation, extraction of features from optic disc region of interest and classification for detection of glaucoma. The main novelty of the proposed method lies in the formation of a feature vector which consists of spatial and spectral features along with cup to disc ratio, rim to disc ratio and modeling of a novel mediods based classier for accurate detection of glaucoma. The performance of the proposed system is tested using publicly available fundus image databases along with one locally gathered database. Experimental results using a variety of publicly available and local databases demonstrate the superiority of the proposed approach as compared to the competitors.
Medical image analysis is a very popular research area these days in which digital images are analyzed for the diagnosis and screening of different medical problems. Diabetic retinopathy (DR) is an eye disease caused by the increase of insulin in blood and may cause blindness. An automated system for early detection of DR can save a patient's vision and can also help the ophthalmologists in screening of DR. The background or nonproliferative DR contains four types of lesions, i.e., microaneurysms, hemorrhages, hard exudates, and soft exudates. This paper presents a method for detection and classification of exudates in colored retinal images. We present a novel technique that uses filter banks to extract the candidate regions for possible exudates. It eliminates the spurious exudate regions by removing the optic disc region. Then it applies a Bayesian classifier as a combination of Gaussian functions to detect exudate and nonexudate regions. The proposed system is evaluated and tested on publicly available retinal image databases using performance parameters such as sensitivity, specificity, and accuracy. We further compare our system with already proposed and published methods to show the validity of the proposed system.
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