Background::
Currently, developing methods for the formation of nanoparticles with antimicrobial properties
based on green chemistry are the research hotspots. In this research green biosynthesis of Eriobotrya japonica extract loaded
silver nanoparticles and their characterization were the main objectives to achieve.
Methods::
Green synthesis of E. japonica leaves extract-loaded silver nanoparticles (AgNPs) was carried out and its effect
on bacterial growth was examined. The reduction of silver ions in solution was observed using UV-Vis spectrophotometer.
The properties of AgNPs were assessed using Scanning electron microscopy (SEM), Fourier transform infrared
spectroscopy (FTIR) and X-ray diffraction (XRD). Also, their antibacterial effects were checked against Staphylococcus
aureus and Escherichia coli.
Results::
It was revealed that 5-50 nm sized spherical to elongated nanoparticles were synthesized that possessed
comparatively better antibacterial potential against E. coli and S. aureus than conventional extract of the E. japonica leaves.
Conclusions::
Green synthesis and effective utilization of Eriobotrya japonica extract loaded silver nanoparticles is a
promising approach for nanoparticle production avoiding negative environmental impacts.
The anticancer and anti-inflammatory activities of wild-sage (Lantana camara) leaves essential oil were evaluated against various human cell lines. In this regard, steam hydro-distillation technique was used for oil extraction. Chemical characterization of L. camara essential oil (LCEO) was done by GC-MS, and forty one chemical components (98.69%) were detected in leaves of LCEO. The major constituents were caryophyllene oxide (19.63%), caryophyllene (6.68%), β-phellandrene (6.48%), humulene epoxide II (5.68%), spathulenol (4.17%), α-pinene (3.27%), eucalyptol (3.09%), α-cyclocitral (2.89%), β-pinene (2.38%), and nerolidol II (2.33%). Moreover, the antioxidant and antimicrobial potential of LCEO were also examined. LCEO also showed good anti-inflammatory activity. Interestingly, it was found that the L. camara essential oil was active against a set of microbial strains along with promising antioxidant activity. The MTT assay showed that LCEO possessed good anticancer potential against U-266, A-549, HCT-116, SCC-4, MiaPaCa 2, and KBM-5 cancer cell lines. In these cell lines, it was depicted that the LCEO blocked the tumor cell proliferation via NF-κB pathway suppression. The promising and potent bioactivities of LCEO support the candidature of these essential oils as an anticancer agent.
In this article, a DFT study is carried out to explore the electronic, structural and optical properties of SrZrO3 (SZO). Zn is doped at Sr site in minimum quantity to explore the minimal effect of Zn on electronic behaviour and its impact on other properties. For investigation of these properties, Ultrasoft pseudopotentials (USP) and Generalized Gradient Approximation suggested by Perdew, Burke, and Ernzerhof (GGA-PBE) functional is executed. The inclusion of Zn at Sr site in SZO affects the electronic and optical properties significantly. Band gap was expressively reduced from 3.315 eV to 2.618 eV which has direct impact with interacting energies. The nature of band gap for both intrinsic and doped systems remain indirect which means Zn inclusion did not affect the nature of band gap. The change in electronic properties due to addition of impurity leads towards change in optical properties. All the optical properties including complex dielectric function, absorption spectra, reflection coefficient, refractive index and extinction coefficient were calculated. The results showed a clear red shift in the absorption spectra along with peak shifting from 2.98 eV to 0.63 eV and the refractive index obtained for pure material is 2.13 which then altered to 2.45 due to doping. Doping of zinc in SZO significantly alter the electronic and optical properties and thus making it a valuable asset for optoelectronic devices.
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