Negative pressure pulmonary edema (NPPE) in the context of anesthesia is a rare condition, although pediatric patients are at higher risk. This case stands out for the severe respiratory clinic that quickly developed in a child with a cancer history whose radiological and clinical presentation suggested multiple differential diagnoses, including tumor recurrence with metastasis or pulmonary tuberculosis. NPPE is a well‐described, but a probably underrecognized clinical syndrome, that occurs after intense inspiratory effort against an obstructed airway. In clinical practice, when unexplained pulmonary edema takes place, NPPE should be considered in the differential diagnosis. NPPE usually has a favorable prognosis but pediatricians, radiologists, and anesthesiologists should be aware of this complication.
antibacterial component (for the treatment of purulent inflammation), as well as cerumenolytics for cleaning of the external auditory meatus and the prevention of external otitis and conductive hearing loss. Within 6 months of observation a positive tendency was noted.The child was referred to a geneticist. Mutation was detected in exon 2 of the EDA genec.466C> T in a homozygous state and the diagnosis of hypohydrotic ectoderm dysplasia was confirmed. Vaccination against Str.Pneumoniae and H. influenzae type b was recommended for the prevention of frequent respiratory infections. Conclusions The treatment of children with hypohydrotic ectoderm dysplasia is complex and includes thorough skin and mucous membrane care, vaccination to prevent respiratory infections and development of complications. For early diagnosis and the correct treatment of patients, the awareness of pediatricians and other specialists of the symptoms of rare hereditary diseases as well as interaction with geneticists are of utmost importance.
Considering previous reactions, laboratory findings and results of the oral challenge test, we suggest that our patient meets the criteria for DIES by amoxicillin. We performed a comprehensive literature search and found three cases of DIES reported in children and one in an adult patient who developed a severe reaction with shock.In our opinion, the clinical awareness on DIES and its potential severity should be improved and it is important to distinguish it from side effect of the drug.
second group possessed higher values of all parameters in comparison to those from the first and the third groups.Lesser development of bone tissue revealed by a decreased arm length and size of the major joints probably reflect the anti-androgenic effect of OCPs before and during puberty in males of the first group, while the opposite trend revealed in females from the second group may result from estrogenic effect of mild doses of OCPs. Differences in body mass, waist perimeter and skinfold thickness possessed by volunteers from regions with different environmental conditions may reflect the previously described influence of endocrine disruptor chemicals, such as OCPs, on the balance of leptin, whose functions are established in puberty.
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