OBJECTIVE: to assess the effectiveness of 2% papain gel compared to 2% carboxymethyl cellulose in the treatment of chronic venous ulcer patients. METHOD: randomized controlled clinical trial with 12-week follow-up. The sample consisted of 18 volunteers and 28 venous ulcers. In the trial group, 2% papain gel was used and, in the control group, 2% carboxymethyl cellulose gel. RESULTS: the trial group showed a significant reduction in the lesion area, especially between the fifth and twelfth week of treatment, with two healed ulcers and a considerable increase in the amount of epithelial tissue in the wound bed. CONCLUSION: 2% papain gel demonstrated greater effectiveness in the reduction of the lesion area, but was similar to 2% carboxymethyl cellulose gel regarding the reduction in the amount of exudate and devitalized tissue. Multicenter research is suggested to evidence the effectiveness of 2% papain gel in the healing of venous ulcers. UTN number: U1111-1157-2998
Aim: to describe the main characteristics of Brazilian nursing and health groups registered in the Research Group Directory in Brazil involved in the study of wound care. Method: This is a documentary study which adopts a transversal approach, performed between March 3rd and April 10th 2012, with information collected from research groups that study wound care. Results: Of the 61 selected groups, 42.6% are located in the Southeast region of Brazil; only 44.26% of the groups have nursing staff involved. The majority of the group leaders are medical doctors; 78.7% of the groups have developed up to seven lines of research. Of these, 31.8% of the lines of research focus on histopathology and wound healing. Conclusion: Nursing staff develop many lines of research in the area of assistance and quality of life, but there is a significant paucity of research based on an interdisciplinary context.
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