The changes reported herein might influence the selection of the dental materials and will bring new knowledge in this field to prevent radiation-related caries in root dentin.
Purpose: The purpose of this study was to conduct a critical literature review on oral conditions and dental phenotypes
described in patients with Syndromic Pierre Robin Sequence (SPRS). The review of theMaterials and Methods:
literature on oral conditions and dental phenotypes was performed in patients with SPRS through an active search in three databases, PubMed,
Medline and SciELO, using the descriptors: “Dental Abnormalities”, “Tooth Abnormalities”, “Oral Diagnosis”, “Dentistry”, “Oral Health”,
combined with: “Pierre Robin Syndrome”, “Mandibulofacial Dysostosis”, “22q11 Deletion Syndrome”, and “Stickler”. For the selection of
manuscripts, papers published between 2014 and 2022 were analyzed according to the inclusion criteria. Were selected 7 studiesResults:
addressing dental conditions or dental anomalies in SPRS in the 3 syndromes chosen: 22q11.2 Deletion Syndrome (22q11.2 DS), Treacher
Collins Syndrome (TCS) and Stickler Syndrome (SS). In the 3 studies on 22q.11 DS, it was observed that the most reported anomalies were
dental agenesis, impacted canine, enamel hypoplasia and supernumerary tooth, respectively. In studies on TCS, with a reduced number of
subjects, dental crowding and occlusal changes were the most common oral conditions. No study addressed the dental phenotypes of SS.
Conclusions: The importance of further studies on this specic topic is emphasized, since SPRS involves micrognathia and mandibular
retroposition. Thus, these clinical ndings can be valuable for all professionals who provide assistance to these patients. Thus, based on this
knowledge, it is possible to plan more effective rehabilitation, contributing to improving the quality of life of these individuals.
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