The aim of the present research was to evaluate the potential of Nectomys rattus, the "water rat", to develop Schistosoma mansoni infection. Comparison Key words: Nectomys rattus -Nectomys squamipes -wild rodent -Schistosoma mansoni -experimental infectionThe occurrence of wild populations of small rodent naturally infected in endemic schistosomiasis areas had been considered as an additional complication factor for the control of the disease (Rey 1993).The species Nectomys squamipes, the "water rat", is one of the most important non-human hosts for Schistosoma mansoni in Brazil (Antunes et al. 1973, Picot 1992. This species excretes viable eggs of the parasite during its hole life-span (RodriguesSilva 1988) and shows strong fitness to parasitism . Furthermore, N. squamipes has a high susceptibility to experimental infection (Souza et al. 1992), reinfection (Maldonado Jr. et al. 1994), and with a moderate pathogenic response (Silva & Andrade 1989 at the eastern Brazilian coast, from north of the municipality of São Lourenço da Mata (State of Pernambuco) to the Amazon river. That new given designation is N. rattus (2n=52).N. squamipes (2n=56) distribution has been restricted to the Atlantic coast of Brazil, in the basins of São Francisco river and Paraná river, as well as in the small independent basins of southern São Lourenço da Mata, in eastern Brazil.The broad distribution of N. rattus includes endemic areas of schistosomiasis apart from those where N. squamipes are found. However, there have been only two reports where N. rattus (formerly named N. squamipes amazonicus) were found naturally infected (Bastos et al. 1982(Bastos et al. , 1984.The aim of this research was to evaluate the potential of N. rattus to develop S. mansoni infection, and its ability to complete the parasite's life cycle under experimental conditions. All results were compared to the N. squamipes relation with S. mansoni infection. MATERIALS AND METHODSExperimental groups -Thirty seven specimens of N. rattus and 58 specimens of N. squamipes of both sexes, aged 3 to 5 months and weighing 250 to 300 g were used. All experimental animals were raised in our laboratory colonies (D'Andrea et al. 1996). The colony of the N. rattus derived from animals captured in the State of Goiás
The seroprevalence of toxoplasmosis in 832 pregnant women in Miracema, Rio de Janeiro, was determined and 75.1% (625) The parasite Toxoplasma gondii is one of the most frequent to infect human beings and is found in almost one-third of the world population (Dubey 2004). Patients are frequently asymptomatic and toxoplasmosis has no relevant repercussions on the patient. However, infected fetuses and immunodeficient individuals may present with serious or even fatal clinical outcomes (Gross 1996, Vidigal et al. 2002. Toxoplasmosis infection is transmitted (1) by the ingestion of raw or undercooked meat, which contains tissue cysts of the parasite; (2) through the accidental ingestion of oocysts eliminated in the feces of infected cats; and (3) transplacentary due to the primary gestational infection (Frenkel et al. 1970, Hutchinson et al. 1971, Aspinall et al. 2003, Bahia-Oliveira et al. 2003.The diagnosis of toxoplasmosis is based mainly on serological tests that detect anti-T.gondii IgM and IgG antibodies (Camargo 1995, Pinard et al. 2003, that correspond to acute and chronic infections, respectively. Although IgM anti-T. gondii (IgMTg) tend to disappear, it can remain at low titers for a long period of time complicating the interpretation of the serological diagnosis of the acute phase in that case they are named residual IgM and correspond to the chronic phase of the disease (Bastien 2002, Remington et al. 2004. In order to differentiate the two phases, an important step in defining In the present report, the prevalence of residual IgM in pregnant women from Miracema, Northwest of the state of Rio de Janeiro, Brazil (Table I) was investigated, as well as the correlation of these antibodies with IgG avidity, in the patients and in their family groups, in order to effectively establish the diagnosis of acute or chronic toxoplasmosis. The studied sample was chosen considering an estimated prevalence (IgGTg) of toxoplasmosis of 75% in order to identify the "n" value necessary to obtain enough seronegative individuals to ensure that 25% of the sample would be candidates for being IgMTg positive during pregnancy. Consequently, in order to determine the sample size, the population of women in the municipally (n = 13521), a prevalence of 25%, an estimated error of 3%, and a significance level of 5% were considered as parameters leading to a minimum sample of 756 pregnant women. Thus, from May 2003-December 2006, 832 pregnant women that visited the municipal public health system were selected and evaluated.Serological tests were performed in order to detect IgMTg and IgGTg antibodies using a commercial enzyme linked immunosorbent assay Diesse® (ELISA) kit in all pregnant women. This technique has 100% and 99.6% specificity and sensitivity, respectively, for detecting IgMTg and has 100% for both analytical parameters for IgGTg. The patients that were IgMTg and IgGTg posi-
Resumo O racismo está enraizado na sociedade brasileira, sendo relevante discutir e promover ações antirracistas e de valorização da população negra. O ensino da temática “relações raciais” é importante instrumento para estimular essas ações, principalmente no âmbito dos programas de pós-graduação (PPGs) stricto sensu da área pública no Brasil. Assim, mediante pesquisa estatística-descritiva e análise documental, tais programas foram estudados e concluiu-se que a maioria dos que abordam a temática racial direta e/ou indiretamente em suas disciplinas está ligada às políticas públicas, enquanto o debate é secundarizado na maioria dos PPGs de Administração e Gestão Pública. Ademais, há uma tendência da não obrigatoriedade curricular de disciplinas que fazem referência direta à discussão racial.
Objetivo: analisar como a encontrabilidade da informação pode colaborar para a disseminação dos documentos da Comissão da Verdade da Universidade Federal do Rio Grande do Norte. A metodologia: caracteriza-se como bibliográfica e documental, desenvolvida por meio do método indutivo, de abordagem qualitativa. Os principais resultados alcançados foram: o mapeamento dos documentos da Comissão da Verdade da Universidade Federal do Rio Grande do Norte que estão no Laboratório de Imagens, e os que estão no Arquivo Geral da universidade. Diante disso, reflete-se nas conclusões: a necessidade de contribuir para a publicização dos referidos por meio da utilização dos atributos de encontrabilidade da informação. Nessa perspectiva, recomenda-se a criação de um Repositório Digital e a criação de um acervo especial composto pelos documentos da Comissão da Verdade da Universidade Federal do Rio Grande do Norte no Arquivo Geral e/ou na Biblioteca Central Zila Mamede.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
334 Leonard St
Brooklyn, NY 11211
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.