Background The aim of this study was to determine the relative frequency of primary cutaneous lymphoma (PCL) in Argentina according to the new World Health Organization (WHO)-European Organization for the Research and Treatment of Cancer (EORTC) classification system.Methods A total of 416 patients from 21 dermatology services were included during a 5-year period (2010-2015); these patients were classified using WHO-EORTC criteria.Results There were 231 (55.2%) males and 185 (44.8%) females; the male-to-female ratio was 1.35. The median age of the patients was 57 years (range, 0-90 years). Most patients were Caucasian (79%), and only 16% of patients were registered as Amerindian. Most patients (387/416, 93%) had cutaneous T-cell lymphoma (CTCL); 28 patients (6.7%) were diagnosed with cutaneous B-cell lymphoma (CBCL). The most frequent CTCL subtypes, in decreasing order of prevalence, were mycosis fungoides (MF), including its variants (75.7%); CD30+ primary cutaneous lymphoproliferative disorders (7.2%); and S ezary syndrome (SS) (3.1%). Cutaneous follicle center lymphoma was the most common CBCL subtype (2.9%). In the subset of patients ≤20 years of age, the most common condition was MF (57%), followed by extranodal NK-T nasal-type lymphoma (14%). ConclusionsThis study revealed relatively higher rates of MF and lower rates of CBCL in Argentinean patients that have been reported in American and European countries.

El queratoacantoma solitario es un tumor queratinocítico localizado en zonas fotoexpuestas que se caracteriza por tener tres fases evolutivas: una primera de crecimiento rápido, una de estabilidad y una final de involución espontánea. Esta última no se observa con tanta frecuencia porque su diagnóstico diferencial, el carcinoma espinocelular, obliga a que la terapia de elección sea la escisión quirúrgica. La decisión de mantener una conducta expectante debe tomarse en conjunto con el paciente, quien debe conocer los riesgos que esta implica. Presentamos los casos de 2 pacientes que rechazaron la opción quirúrgica y tuvieron una evolución favorable con una estricta supervisión clínica.

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