<p><strong>Objetive:</strong> The purpose of this study is was to evaluate the influence of sandblasting ceramic and enamel structure on bond strength, changing distance.</p><p><strong>Material and methods:</strong> 60 third molars , were selected, enamel surfaces were ground flat with wet 600 - 2000 grit aluminum oxide abrasive papers and polished with three, one, and one-fourth micrometer-grit diamond pastes. Obtained 120 lithium disilicate-based core ceramic discs ( 2 mm diameter;1 mm thickness), divided into 7 groups [Group C, don’t sandblasting, Group SB-E(5-10) enamel sandblasting 5 and 10 mm, Group SB-C(5-10) ceramic sandblasting 5 mm and 10 mm, Group SB-EC(5-10) enamel and ceramic sandblasting 5 mm and 10 mm] after was performed microshear and Atomic Force Microscopy (AFM), Statistic Teste of normality , after one-way ANOVA and Tukey test (α: 0.05).</p><p><strong>Results:</strong> The group C present bond strength (59.2±12.5), the group SB-E 5 mm (21.7±08.8) (p<0.005), the group SB-E10 (53.6±14.3).</p><p><strong>Conclusion:</strong> The use of sandblasting treatment of the enamel surface a 5 mm by 20 seconds decreases the bonding strength to microshear.</p>
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