From their first contact with continuously cultured ZF4 cells, 10, 30 and 100 nm PVP-capped AgNPs induce receptor mediated endocytotic processes, cellular repair mechanisms, and at higher doses, cell death via autophagy, apoptosis or necrosis.
This study compared results of nanoparticle number concentration measurements collected from 74 instruments hosted across 50 laboratories, providing users with useful discussion and reference data to assess and benchmark their measurement capability.
The dynamic interplay between toxicity pathways (oxidative stress, calcium disturbances, genetic damage) caused by nanoparticles and the repair mechanisms of inhibition of cell division and induction of cell death is explored in zebrafish embryo cells.
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