This research proposed an innovative way of protecting pregnant woman from potential risky drugs by implementing clinical reminder system based on health smart card. A computerized risky drug reminders system for pregnant woman on the Computerized Physician Order Entry (CPOE) was implemented. During the study period, there were 1106 pregnant women visits and ranged in age from 15 to 50 years. Significant effect in physicians' specialty, seriousness of risky drugs, and trimesters of pregnant woman were found. X category drugs are observed with more relevant to the clinical settings and with higher acceptance rate (22.39%). Physicians other than obstetrics and gynecology, dermatologist, endocrinologist are with higher acceptance to the reminders (46%). Pregnant woman in first trimester (19.39%) are with more concerns and also with highest acceptance rate on the risky drug reminders.
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