2Stroke is the leading cause of adult disability worldwide, with up to two-thirds 3 of individuals experiencing long-term disabilities. Large-scale neuroimaging 4 studies have shown promise in identifying robust biomarkers (e.g., measures 5 of brain structure) of long-term stroke recovery following rehabilitation. 6However, analyzing large rehabilitation-related datasets is problematic due to 7 barriers in accurate stroke lesion segmentation. Manually-traced lesions are 8 currently the gold standard for lesion segmentation on T1-weighted MRIs, but 9 are labor intensive and require anatomical expertise. While algorithms have 10 been developed to automate this process, the results often lack accuracy. 11Newer algorithms that employ machine-learning techniques are promising, yet 12 these require large training datasets to optimize performance. 1.1 will be a useful resource to assess and improve the accuracy of current 19 lesion segmentation methods.

Greater numbers of persons will enter retirement outside of marriage or with a checkered marital history. Given the traditional health benefits of marriage, these changes in the population's marital life course may foretell changing demands for eldercare in addition to adverse health consequences. Here, the authors provide new evidence on the specific aspects of health associated with marriage for a nationally representative survey of retirement age adults. An important aspect of the authors' analysis is the assessment of whether the benefits of marriage hold equally for women and men, major race/ethnic groups, and persons with different marital histories. Data from the Health and Retirement Survey are used to evaluate how marriage is associated with major chronic illnesses, functional limitations, and disability. Findings document that marriage benefits health across a broad spectrum of fatal and nonfatal chronic disease conditions, functioning problems, and disabilities. Moreover, benefits of marriage are widely shared across demographic groups.

We explore women's psychological well-being in late midlife in relation to childlessness and timing of entry into motherhood. Using two U.S. surveys, Health and Retirement Study (HRS) (1992) and National Survey of Families and Households (NSFH) (Sweet, Bumpass, & Call, 1988), we assess the well-being of childless women in their 50s compared to mothers with early, delayed, or normatively timed first births. We focus on the cohorts born between 1928 and 1941, who experienced strong normative pressures during the baby boom with regard to marriage and child-bearing. We find few differences among childless women but lower well-being among early mothers, related to singlehood and poorer socioeconomic status. Unmarried mothers are significantly disadvantaged regardless of maternal timing, controlling for socioeconomic status. Current maternal demands are independently related to well-being and help to explain observed differences in family satisfaction. Overall, childlessness and off-time child-bearing are related to midlife well-being through their link with more proximate factors, particularly current marital status, health, and socioeconomic status.

The purpose of this study was to develop and evaluate a model of labor force participation among a group of older women in the United States. A comprehensive measure of women's combined work and family experiences across the adult life course was created. Employing data from the 1984 Survey of Income and Program Participation, we applied multinomial logistic regression techniques to examine the association between work-family experiences and later life labor supply. Our findings generally support an attachment hypothesis, showing that women who were the most work-oriented throughout the life course were more likely than women who experienced family-related spells of nonlabor-market activity to participate in the labor force, either full-time or part-time, later in life.

The purpose of this study is to examine alternative pathways to labor force exit among older men. Based on the life course perspective, we distinguish between crisp exits from the labor force, which are characterized as being unidirectional, and blurred transition patterns, which include repeated exists, entrances, and unemployment spells. Using longitudinal data from the 1984 Survey of Income and Program Participation, we find that one-quarter of the sample of men aged 55 to 74 at first interview experienced at least one transition in labor force status over a 28-month observation period. Fewer than half of these can be characterized as crisp exists from the labor force. Our multivariate analysis suggests that blurred transition patterns are likely part of an effort to maintain economic status in later life.

Stroke is the leading cause of adult disability worldwide, with up to two-thirds of individuals experiencing long-term disabilities. Large-scale neuroimaging studies have shown promise in identifying robust biomarkers (e.g., measures of brain structure) of long-term stroke recovery following rehabilitation. However, analyzing large rehabilitation-related datasets is problematic due to barriers in accurate stroke lesion segmentation. Manually-traced lesions are currently the gold standard for lesion segmentation on T1-weighted MRIs, but are labor intensive and require anatomical expertise. While algorithms have been developed to automate this process, the results often lack accuracy. Newer algorithms that employ machine-learning techniques are promising, yet these require large training datasets to optimize performance. Here we present ATLAS (Anatomical Tracings of Lesions After Stroke), an open-source dataset of 304 T1-weighted MRIs with manually segmented lesions and metadata. This large, diverse dataset can be used to train and test lesion segmentation algorithms and provides a standardized dataset for comparing the performance of different segmentation methods. We hope ATLAS release 1.1 will be a useful resource to assess and improve the accuracy of current lesion segmentation methods.

Husbands and wives both respond to individual and joint constraints and opportunities when planning for retirement. Findings support that there is considerable overlap in retirement planning of husbands and wives during early parts of the retirement decision-making process. However, inequity in cross-spousal influences is a defining characteristic of retirement decision making. Implications for both policy makers and practitioners are briefly discussed.

The purpose of this research is to evaluate the consequences of early childbearing decisions for women's labor force activity in later life. Within a life course framework, women's early childbearing activities may be linked to later life decisions. Women between ages 55 and 64 are evaluated from the 1984 Survey of Income and Program Participation. Two measures of early family roles are considered: total fertility (number of children ever born) and timing of first-birth (childless, prior to age 30, and 30+). Results provide some limited support that early childbearing roles do in fact have a long-term impact on the employment decisions of women. Women who delay childbearing are somewhat more likely to remain in the labor force during their later years whereas women who remain childless are more likely to have exited the labor force.