The second case of Bordetella holmesii endocarditis in a pediatric patient is presented. This patient had a prosthetic mitral valve and asplenia. He was successfully treated with 6 weeks of intravenous meropenem. We review all 9 other reported cases of endocarditis and summarize treatment and outcome. Five were immunocompromised and 6 had predisposing cardiac conditions.
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