A cyanobacterium is the simplest organism to have a circadian clock (Iwasaki and Kondo, 2004). Circadian clocks consist of 3 major components: a central oscillator, an input pathway, and an output pathway (Takahashi, 2004). The central oscillator in cyanobacteria is known as the minimal self-sustained circadian oscillator and is composed of 3 proteins, KaiA, KaiB, and KaiC. The oscillator can be reconstituted in vitro by mixing the Kai proteins with adenosine triphosphate (ATP) and magnesium (Kim et al., 828068J BRXXX10.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.