This paper develops the concept of implicit trait policy (ITP), which is a variant of the accentuation effect described by Tajfel (1957). ITPs are implicit beliefs about causal relations between personality traits and behavioral effectiveness. Studies reported here tested the hypotheses (a) that personality traits affect ITPs so that agreeable people, for instance, believe the relation between agreeableness and effectiveness is more strongly positive than disagreeable people do and (b) that ITPs can predict behavior that expresses associated personality traits. Two studies with undergraduate research participants supported the first hypothesis for traits of agreeableness and extraversion (the average correlation between traits and associated ITPs was .31 for agreeableness and .37 for extraversion) but not for conscientiousness. A 3rd study with student participants found that individual differences in ITPs for agreeableness predicted agreeable behavior (the average correlation was .33) in simulated work settings. These results suggest that ITPs may be useful for predicting work behavior that expresses personality traits even though ITPs may not be strongly correlated with the personality traits themselves.

BackgroundAltered expression of mRNA splicing factors occurs with ageing in vivo and is thought to be an ageing mechanism. The accumulation of senescent cells also occurs in vivo with advancing age and causes much degenerative age-related pathology. However, the relationship between these two processes is opaque. Accordingly we developed a novel panel of small molecules based on resveratrol, previously suggested to alter mRNA splicing, to determine whether altered splicing factor expression had potential to influence features of replicative senescence.ResultsTreatment with resveralogues was associated with altered splicing factor expression and rescue of multiple features of senescence. This rescue was independent of cell cycle traverse and also independent of SIRT1, SASP modulation or senolysis. Under growth permissive conditions, cells demonstrating restored splicing factor expression also demonstrated increased telomere length, re-entered cell cycle and resumed proliferation. These phenomena were also influenced by ERK antagonists and agonists.ConclusionsThis is the first demonstration that moderation of splicing factor levels is associated with reversal of cellular senescence in human primary fibroblasts. Small molecule modulators of such targets may therefore represent promising novel anti-degenerative therapies.Electronic supplementary materialThe online version of this article (10.1186/s12860-017-0147-7) contains supplementary material, which is available to authorized users.

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Pearlman, Schmidt, and Hunter (1980) published a seminal paper on the validity of various measures for predicting performance in clerical jobs. They concluded that for both job and training performance criteria, 10 types of tests (e.g., perceptual speed, clerical aptitude, verbal ability) predicted performance across 5 clerical job families. This paper describes a psychometric meta-analysis of validity studies using similar measures for clerical jobs conducted since 1980 to examine the stability of Pearlman and colleagues' validity estimates. This paper contributes to the literature by investigating the long-term stability of validity generalization estimates over a period of several decades. Clerical jobs provide a compelling case study because these jobs have changed considerably due to the increased use of computers and technology in the office environment. Results showed that the mean population estimates in the present study were consistent with, or higher than, those obtained by Pearlman and colleagues, thus demonstrating the long-term stability of metaanalytic estimates of validity. The relative stability of the validity estimates also supports the robustness of g as a predictor, even as jobs change over time.