Puffer fish (Lagocephalus sceleratus) is a well-known source of deadly food poisoning due to a neurotoxin, called tetrodotoxin. Cases of tetrodotoxin poisoning are common along the coasts of East Asian countries but rare in the Arabian Gulf region. Here, we report a case of a 19-year-old man who presented with signs and symptoms suggestive of puffer fish poisoning. Dietary history was the key to diagnosis though laboratory investigations and imaging yielded normal results. Early diagnosis and proper supportive management are essential for survival.
Crouzon's syndrome is a rare autosomal dominant disorder characterized by craniofacial malformations.It's the most common syndrome among the craniosynostosis group accounting for about 4.8 % of all of them. Crouzon syndrome is caused by mutation in the fibroblast growth factor receptor-2 (FGFR-2) gene resulting in premature closure of suture lines. Our article describes a case report of a 3 years old girl who displayed characteristic dysmorphic skull and facial features of Crouzon's syndrome.
significantly greater rates of catastrophic expenditures (12.75% versus 8.33% with and without cancer, respectively, p[0.0273). Significant predictors of catastrophic expenditures in bladder cancer survivors included older age, comorbid illnesses, lower income, retirement, poor health status, and private insurance (Table 1). Among white patients, a bladder cancer diagnosis was not associated with increased odds of catastrophic expenditures (9.18% vs. 8.65%, OR 1.08, 95% CI 0.742 -1.578), while in Black patients bladder cancer was associated with significantly increased odds of catastrophic expenditures (19.49% vs. 5.14%, OR 6.41, 95% CI 1.28 e 32.01, Figure 1).CONCLUSIONS: Bladder cancer survivorship is associated with a significant ongoing risk of catastrophic healthcare expenditures, particularly among Black patients. Interventions to mitigate disparities in the burden of cost should account for these differences in risk.
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