BackgroundIncreasing prevalence of type 2 diabetes mellitus (DM) has become alarming, burdening health care systems throughout the world. Prediabetes is an intermediate step before manifestation of full blown DM. Effective intervention at this step would help stop/slow progression to DM.ObjectiveThis study aimed at use of a polyherbal combination (PDBT – constituted of Tinospora cordifolia, Pterocarpus marsupium, Gymnema sylvestre, Zingiber officinale and Momordica charantia) along with life style modification compared to a placebo in prevention of DM among prediabetic individuals.Materials and MethodsThe study was a double blinded, placebo controlled randomized clinical trial. Participants were divided in to a group on PDBT and life style management (LSM) and second on placebo and LSM. Participants in the intervention group received 2 gm/day of PDBT. All participants received the intervention for a period of 6 months.ResultsOne hundred and fourteen participants were enrolled in the study, 57 each in intervention and control group. At the end of the study, 8 participants from the intervention group, compared to 15 participants in the control group had converted to DM. There was a 47% risk reduction in the intervention group. Participants in the intervention group showed statistically significant decrease in their blood glucose level (fasting and PP), HbA1c, fasting serum insulin and HOMA-IR values. There was no significant change in BMI. No adverse effects were reported by any participants.ConclusionPDBT along with LSM in prediabetic participants was associated with reduction in conversion to DM than placebo along with LSM without any adverse effects.
Guillain-Barre syndrome is an acute, frequently severe and fulminant polyradiculopathy that is autoimmune in nature. Guillain Barre syndrome is a rare disorder that causes immune systems to attack peripheral nervous system (PNS). A 46 year old male patient, presenting with sudden onset, complete paralysis of all four limbs (quadriplegia), unable to walk, stand, sit, difficulty in deglutition (dysphagia) and dysarthia, was having foley's catheter and Ryle's Tube brought by relative to Out Door Patient Department (OPD) of Government Ayurvedic Hospital, Nagpur; He was provisionally diagnosed as subacute sensory motor paraplegia. Previously patient admitted and treated in Government Medical College (GMC) Nagpur but did not show any sign of improvement so patient was admitted and treated with Ayurvedic treatment for about 50 days. As per Ayurvedic classics, this condition can be correlated with sarvāṅ gagatavātavyādhi (~vāta disorder affecting all parts of the body), which is apatarpaṇa in nature (~diseases with deprived nourishment of body tissue) preceded by jvara (~(H/O fever before onset of GBS). Hence, the principle of treatment is santarpaṇa cikitsā (~nourishing treatment). Santarpaṇa (~nourishing treatment) includes bahyopakramas (~nourishing external treatment modalities), such as abhyaṅga (~oleation therapy) and ṣaṣṭikaśālipiṇḍasveda (~sudation using of hot and processed ṣaṣṭika rice), karmabasti (~medicated enema) śirodhārā (gentle pouring of medicated liquid over forehead) and jvaraghna cikitsā (~treatment of fever) using various Ayurvedic herbomineral compounds. Remarkable results were observed in the form of improvement in the muscle power from zero to five of all four limbs with improvement in speech. There was no difficulty post treatment in deglutition, sitting, standing and walking; and now patient has near to normal movements.
Gomutra is important part of Indian tradition. It is not only holy but also has various important medicinal uses. Classical treatises in Ayurved i.e. Charaka, Sushruta and Vagbhata Samhita has described Ashta mutra (eight types of urine) along with their properties, indication and formulations. Cow urine is one of them. Cow urine is one of the five contents of Panchagavya which obtain from cow (urine, milk, ghee, curd and dung). Cow based treatment is called as Panchagavya Chikitsa (Cowpathy). In this modern era, the diseases related to life style like cancer, autoimmune diseases, diabetes, AIDS etc. are increasing day by day. Irrational use of antibiotics is also responsible for increase in antibiotic resistant infectious diseases. Gomutra (Cow urine) is scientifically proven to act as an immunomodulator along with its bacteriostatic action. Various actions and researches on cow urine are summarized in this article. However, more studies experimental as well as clinical can throw better light on it.
Purpose Covid 19 pandemic has placed challenges in front of medical health sciences in terms of management, prevention and immunity building. Effectiveness of any medication has not conclusively proven; hence there is need for integrative management of covid 19. We have managed a critical case of covid-19 having history of thalassemia, hypothyroidism with integrative management of Ayurveda and modern medicine. Method A 59 years’ male patient with history of thalassemia had complaints of cough and breathlessness since 4 days. He performed RT PCR because he came in close contact with his daughters who were Covid positive. He was treated with Favipiravir at home for 5 days. He deteriorated on 6 th day with SPO 2 dropped to 75%, temp raised to 101 F and respiratory rate (RR) raised to 45/min. He was admitted in Yogeshwari Hospital Daund, Maharashtra; treated with oxygen inhalation, Remdesvir and Ayurveda medicines in intensive care unit (ICU). Ayurveda treatment protocol was advised through telemedicine. Result Significant improvement in clinical symptoms was observed and normal HRCT was observed after complete treatment. Conclusion This case report gives us further directions for integrative management in cases of Covid 19. Further clinical researches in this direction are warranted.
Sleep is responsible for proper metabolic balance. Disturbances in sleep causes insulin resistance, beta cell dysfunction and obesity through various pathways. Snoring is one of the important indicative symptoms of sleep apnoea that leads to disturbances in sleep. A 54-years old male patient was presented to Kayachikitsa casualty Government Ayurveda College Nagpur with complaints of snoring, difficulty in breathing while climbing stairs since 10 years. After evaluation he was diagnosed as obese with type 2 Diabetes mellitus (DM). Sleep study revealed presence of sleep apnoea. We treated this patient following the principle of Vyadhi Hetu Sankar (∼one cause for many diseases). In such a case treatment of Hetu (∼cause of disease) can be principle of treatment. Snoring was subsided in patient after one -month of treatment. Significant reduction in HbA1c, fasting and post prandial blood glucose level were observed along with reduction in Lipid levels and BMI in three months. Ayurveda concepts can bring major breakthrough in treatment of metabolic disorders. Various Ayurvedic concepts of gut, lung endocrinal pathways and Agni (∼metabolic power) can generate future studies in this direction.
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