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Background: Sufficient levels of vitamin D (25-hydroxyvitamin D, 25(OH)D) are required during pregnancy to maintain fetal developmental and reduce adverse outcomes in fetus/neonates and mother. The present study aimed to determine the levels of vitamin D in pregnant women and neonates and evaluate the corresponding effects of vitamin D supplementations. Materials and Methods: This descriptive-analytical study, conducted in Asali Hospital, Khorramabad, included 77 pregnant women, between 15e45 years of the age, presented with the gestational age of 37e42. 5cc of the blood samples were obtained from the mothers during the labor and umbilical cord, postpartum. Demographic and medical data were obtained from the patients and results from the lab findings, based on the levels of 25(OH)D, were recorded in the questionnaire. Results: The mean concentration of 25(OH)D in pregnant women was 13 ng/ml and their neonates was 15 ng/ml. Overall, 60.9% of the mothers and neonates were reported to be 25(OH)D deficient whereas, 89% of the mothers and their newborns had insufficient vitamin D levels. The levels of 25(OH)D in the umbilical cord had a significant relationship with serum vitamin D levels. Maternal age, gestational age, body mass index and occupational status had no

Background Peripheral artery disease (PAD) is a cardiovascular disease that is characterized by obstruction of peripheral artery. It is associated with comorbidities, reduced quality of life and mortality. The aim of this study was to determine the frequency of recurrence of PAD among patients who underwent angioplasty or stenting and associated risk factors. Methods In this retrospective study, all patients referred to the cardiovascular center of (XXX) with the diagnosis of lower extremity PAD were included. Patients’ demographic information, age, gender, smoking status, history of diabetes, history of hypertension, dyslipidemia, number of vessels, type of stent, recurrence of the disease, and size of the lesion were obtained from the hospital database. Endovascular revascularization therapy was either performed by angioplasty or stenting method. The data were analyzed by SPSS v21. Results Of 88 patients included in this study, 12.5% were reported with restenosis. Gender, age, size of the lesion, the status of smoking, history of hypertension, and dyslipidemia were not significantly associated with the recurrence of stenosis, p > 0.05. There was a significant relationship between the vessels involved and the type of revascularization method and the recurrence of the PAD. Conclusion Endovascular revascularization technique and type of vessel involved in PAD are significant factors contributing to restenosis in our population of study. However, further studies with a greater sample size are required in this area.

Background & Objectives: Coronary artery disease (CAD) is chiefly characterized by atherosclerosis and plaque formation in coronary arteries. The aim of this study was to evaluate the correlation of coronary anatomy as a predictor of restenosis and stent thrombosis in coronary artery disease (CAD) patients 5 years after percutaneous coronary intervention (PCI). Methods: In this prospective study, 1070 patients with stent restenosis or stent thrombosis over past 5 years were enrolled. Coronary angiography was performed to evaluate coronary restenosis and stent thrombosis 5 years after PCI. Stent restenosis was defined as >50% angiographic in-stent lumen reduction. Stent thrombosis was defined as sudden complete occlusion of stent presenting with acute myocardial infarction in that territory. Demographic data, clinical features and anatomic factors were prospectively reviewed. Baseline, procedural, and post-procedural characteristics of patients were recorded for analysis. Results : Among demographic characteristics, cardiovascular risk factors (hypertension and diabetes mellitus) and anatomic factors were predictive risk factors for restenosis/thrombosis, p=0.001. The most common site for stent restenosis was proximal to the mid part of the LAD artery, followed by RCA and LCX. A greater diameter of LCX, a greater angle of LM-LAD than LM-LCX and left dominancy increase the incidence of LAD stent restenosis/thrombosis. In this study, the least common restenosis/thrombosis rate in relation to the total number of PCI was in the Ramus intermedius artery. Conclusion: The outcomes of the study indicated that anatomic factors can predict increased risk of restenosis among CAD patients who underwent PCI.