Myofacial pain dysfunction syndrome (MPDS) is the most common reason for pain and limited function of the masticatory system. The effects of low-level lasers (LLLs) for controlling the discomfort of patients are investigated frequently. However, the aim of this study was to evaluate the efficacy of a particular source producing 660 nm and 890 nm wavelengths that was recommended to reduce of the pain in the masticatory muscles. This was a double-blind and placebo-controlled trial. Sixteen MPDS patients were randomly divided into two groups. For the laser group, two diode laser probes (660 nm (nanometers), 6.2 J/cm(2), 6 min, continuous wave, and 890 nm, 1 J/cm(2) (joules per square centimetre), 10 min, 1,500 Hz (Hertz)) were used on the painful muscles. For the control group, the treatment was similar, but the patients were not irradiated. Treatment was given twice a week for 3 weeks. The amount of patient pain was recorded at four time periods (before and immediately after treatment, 1 week after, and on the day of complete pain relief). A visual analog scale (VAS) was selected as the method of pain measurement. Repeated-measures analysis of variance (ANOVA), the t-test and the paired t-test were used to analyze the data. In each group the reduction of pain before and after the treatment was meaningful, but, between the two groups, low-level laser therapy (LLLT) was more effective (P = 0.031) According to this study, this type of LLLT was the effective treatment for pain reduction in MPDS patients.

Objective: The aim of this survey is to evaluate the effect of a new developed laser pen as a home care device for patients' pain reduction with recurrent aphthous stomatitis. Background data: Recurrent aphthous stomatitis (RAS) is one of the most common and painful ulcers in the oral cavity. Low Level Laser Therapy (LLLT) has been used successfully for reducing pain and healing time in comparison with corticosteroids and placebo in some studies. But these treatments are done in the clinics and it seems that there is no report of the laser treatment as a home care device up to this study. Methods: This was a prospective, randomized trial pilot study. Thirty patients with RAS were divided into three similar groups. The group one (n = 10) was treated with a diode laser, 660 nm, 40 mw, continuous wave, 1.2 J, 6 J/cm 2 , for five consecutive days (twice per day, 30 seconds each session). The second group (n = 10) was treated with a topical triamcinolone (adcortyl in orabase) ointment four times per day and the third group (n = 10) was treated with placebo (red light pen) the same way as Group 1. All the patients were evaluated with a Visual Analogue Scale (VAS) before and after treatment on the consecutive days. The data was analysed by one way ANOVA and PostHoc tests. Results: The results show that the laser pen and triamcinolon in orabase ointment have similar results and both have better results than placebo in the control of the recurrent aphthous stomatitis pain (p value: 0.001). Conclusion: In this clinical pilot study the laser pen as a home care device seems to be useful for the treatment of RAS.

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Introduction: In some studies, photodynamic therapy with some light sources and light-absorbing materials were used against Candida. In this study, the antifungal effects of 630 nm photosan with different concentrations of methylene blue on Candida albicans that had been grown on dentures was investigated. In data searches no similar study was found. Materials & Methods: This experimental laboratory study was performed in Isfahan Azad University in 2019-2020. On total 26 similar dentures were prepared. Suspension of 0.5 McFarland Candidia albicans was inoculated on the dentures. The samples were put into three groups (seven in each) with different concentrations of methylene blue (0.1, 0.01, 0.001 g/l) and photosan with a wavelength of 630 nm was used. Five control samples including untreated control, photosan alone and three controls with methylene blue concentrations only were considered. The number of colonies was counted using manual and ocular methods. Data were analyzed with T-test, ANOVA. Results: The mean number of Candida albicans grown on dentures after photodynamic therapy and different concentrations of methylene blue was significantly different from control groups (p value < 0.05). The mean number of Candida albicans grown on dentures after photodynamic therapy were significantly different between the three concentrations of methylene blue (p value < 0.001). Methylene blue with a concentration of 0.1 mg had significantly better efficacy against candida compared with two other concentrations (p value < 0.001). Conclusion: Photodynamic therapy with photosan and methylene blue with a concentration of 0.1 provided better results compared to others in reducing Candida albicans.

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Introduction: Recurring aphthous ulcers is a common and painful ulcer in the oral area. The aim of this study was to evaluate the impact of length of radiation in the same dose for the treatment of recurrent aphthous stomatitis. To date no similar study is available. Materials & Methods: In this double-blinded clinical trial, 30 patients with minor aphthous ulcer that were referred to Oral medicine department of Islamic Azad university were selected according to convenience sampling and inclusion exclusion criteria and were randomly divided into two similar groups. Low level laser therapy with diode 660nm was used in group A with 200 mW and 20 seconds setting and in group B with 20 mW and 200 seconds setting in two sessions on the first and third days were used. The time of clinical healing and the pain intensity as VAS were recorded. Data were analyzed by Independent t-test and Mann-Whitney test (p value < 0.05). Results: The pain intensity from first day after the laser until the seventh day in group B was significantly less than group A (p value < 0.001). The mean size of lesion was significantly lower in the third day (p value = 0.03), fifth (p value < 0.001) and seventh (p value = 0.001). The mean clinical healing time in group B was significantly lower than group A (p value < 0.001). Conclusion: According to this study's findings, longer time of irradiation in lower output power of 660 nm diode laser was suggested for treatment of recurrent aphthous ulcer.