SARS-CoV-2 is the causative agent of the global pandemic, also known as Covid-19. This virus belongs to a group of coronaviruses and has affected more than ten million people across the globe, causing nearly half a million deaths worldwide. The pandemic has spread worldwide, originating in the Wuhan Hubei province of China in 2019. The disease is a significant challenge as there is no antiviral treatment. This review will address current trends and emerging new methods for detecting SARS-CoV-2 in the laboratoryat present. Reverse transcriptase PCR or RT-PCR is the gold standard for detecting SARS-CoV-2 disease. The seroprevalence of Covid-19 is performed using antibody detection tests using ELISA and antigen detection as rapid tests. In clinical practice, preliminary disease identification is made based on Chest radiographs, computed tomography, and positron emission tomography (PET) scans. As the pandemic has progressed, newer methods of detection like CRISPR, nanotechnology-enabled solutions, and biosensors have emerged as new methods of detecting SARS-CoV-2.
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Background: Bacterial co-infections with respiratory pathogens are not uncommon. Currently, we are facing the SARS-CoV-2 epidemic, which is a very serious threat to public health. Because TB-Covid-19 infections are a major risk for TB, this is the first report from Afghanistan. Timely and rapid diagnosis of respiratory infections caused by COVID-19, and treatment of tuberculosis patients should be taken very seriously. Methodology: This study was conducted in Afghan Japan Hospital to investigate COVID-19 among 57 tuberculosis patients from April to January 2021, of which 23 patients had extrapulmonary tuberculosis and 34 patients had pulmonary tuberculosis. Nasopharyngeal swabs were taken from all patients and sent to the Microbiology Laboratory of the Hospital for the diagnosis of SARS-CoV-2. It was done using Real-Time Polymerase Chain Reaction (RT-PCR) method. The kit used was from BioVendor. (https://www.biovendor.com). Results: 57 patients with tuberculosis had an average age of 45.5 years. The patients included 29 (16.53%) men and 26 (14.82%) women. 2 people (1.14%) of tuberculosis patients were infection with covid-19. The history of two patients with Covid-19 is as follows. Conclusions: These results indicate the importance of investigating co-infections of covid-19 during the pandemic.
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