Background: Preclampsia is a common disease unique to human pregnancy representing a challenge to obstetricians and neonatologists because of its serious effects on the mothers and babies. We aimed to evaluate hematological and coagulation aspects in newborns of preeclamptic mothers Patients and methods: Sixty (30 full and 30 preterm) neonates delivered to hypertensive mothers and another 30(15 full term and 15 preterm) babies of healthy normotensive mothers were as controls were enrolled. Detailed history taking and full clinical examination were done stressing on parity, mode of delivery, birth weight, APGAR score at o and five minutes and gestational age. All enrolled neonates were subjected to complete blood count (hb,ht,mcv, mch, wbcs, plates), pt, pc and ptt. Results:In full term babies of preeclamptic mothers, primigravida were 70% compared to 20% in controls while In preterm group, prmigravida mothers were 80% compared to 33.3% in controls (p=0.001). Cesarean section was the predominant mode of delivery in preterm neonates to preclamptic mothers (76.6% compared to 13.3% in controls while in full term group, cesarean section was 53.3 % compared to 86.3% for the controls. Sever preeclampsia comprised 80% of mothers of pre term infants versus 33.3% in mothers of term infants APGAR score was lower in infant of preclamptic mothers. RBCs number were and hemoglobin levels were significantly higher in neonates of preclamptic mothers (either term or preterm) than the control (p=0.001) while WBCs were significantly lower in neonates of preclamptic mothers (10.7±2.1,10.8±2.2 and 13.1±1.9,13±1.7respectively) ( p=0.001).Platelets numbers were significantly low in cases (186.1 ±91.5, 133.7 ±58.9) and 223.1 ± 43.4 and 216.4±51.8. Coagulation profile is significantly impaired PT, PTT 28.03±6.9, 21.7±3.1in cases and 14.1±1.8 and13.4±1.5 in controls (p=0.001). Prothrombin concentration was significantly lawer in cases (43.21±78, 61±7.7) compared to controls (70±3.5, 74.2±1.9). Conclusion:Neonates borne to preeclamptic mothers are more susceptible to impaired global coagulation status which is more expressed in preterm babies.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.