The reaction of a number of N-alkyl-3-chloroquinoxaline-2-amines with propargyl bromide in the presence of PdCl 2 (PPh 3 ) 2 and copper(I) iodide in wet morpholine leads to the formation of the unexpected N-substituted pyrrolo[2,3-b]quinoxaline-2-carbaldehydes in good yields. A possible mechanism for the conversion is suggested.
One-Pot Synthesis of 1,2-Disubstituted Pyrrolo[2,3-b]quinoxalines via Palladium--Catalyzed Heteroannulation in Water. -(KEIVANLOO*, A.; BAKHERAD, M.; RAHIMI, A.; TAHERI, S.
Synthesis of Unexpected Pyrrolo[2,3-b]quinoxaline-2-carbaldehydes via Sonogashira Coupling Reaction. -Pd-catalyzed reaction of 3-chloroquinoxalin--2-amines with propargyl bromide proceeds in the presence of wet morpholine to give the title compounds (III) unexpectedly. -(KEIVANLOO*, A.; BAKHERAD, M.; RAHIMI, A.; Synthesis
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