Coronavirus disease 2019 (COVID-19) is a newly-emerging viral illness, affecting primarily the respiratory tract, that has been linked to the occurrence of severe opportunistic fungal and bacterial infections. The incidence of fungal infection increases in patients infected with COVID-19 due to the use of corticosteroids and the accompanying uncontrolled hyperglycemia. We report two cases of acute invasive fungal rhinosinusitis (AIFR): Mucormycosis and Aspergillosis (cases 1 and 2 respectively), diagnosed radiologically and histopathologically. Both cases were treated by a combination of medical treatment and surgical debridement. The first patient improved and was discharged home, while there was a delay in the operation for the second patient who passed away. It is important to raise efforts to adjust hyperglycemia and limit the excessive systematic use of steroids during COVID pandemic to reduce fungal infections.
Coronavirus disease 2019 (COVID-19) is defined as illness caused by a novel coronavirus now called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; formerly called 2019-nCoV), which was first identified as an outbreak in Wuhan City, Hubei Province, China [1]. Cases of multisystem inflammatory syndrome after Covid – 19 infection have been extensively documented in children. CDC reported 27 cases of multisystem inflammatory syndrome in adults (MIS-A) in direct reports through October 2020, as well as various case series and published case reports [2]. Cytokine storm, as a trigger of the progression of HF in patients with COVID-19, has become a novel focus to explore therapies for target populations [3]. In this article, we briefly present a case of a Covid-19 infection associated myocarditis complicated by acute heart failure successfully treated with IVIG.
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