Chemical investigation of butanol and acetone extracts from fresh flowers and aerial parts of Anacyclus cyrtolepidioïdes yielded Rutin 1, Nicotoflorin 2, methyl linoleate 3, a mixture of linoleic, palmitic and linolenic acids 4 indicated for the first time in this specie. The structural elucidations were established by means of efficient methods as 1 and 2D NMR techniques, Gas Chromatography and Electro-Spray Mass Spectrometry. Antifungal activity of both crude extracts and Rutin was studied against four Candida species: C. albicans ATCC 90028; C. glabrata ATCC 90030; C. Krusei ATCC 6258 and C. parapsilosis ATCC 22019 using disc diffusion method. Thus, Rutin was most active against C. albicans specie (20 mm inhibition zone diameter; C=1mg.mL -1 ).
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