The application of data mining, machine learning and artificial intelligence techniques in the field of diagnostics is not a new concept, and these techniques have been very successfully applied in a variety of applications, especially in dermatology and cancer research. But, in the case of medical problems that involve tests resulting in true or false (binary classification), the data generally has a class imbalance with samples majorly belonging to one class (ex: a patient undergoes a regular test and the results are false). Such disparity in data causes problems when trying to model predictive systems on the data. In critical applications like diagnostics, this class imbalance cannot be overlooked and must be given extra attention. In our research, we depict how we can handle this class imbalance through neural networks using a discriminative model and contrastive loss using a Siamese neural network structure. Such a model does not work on a probability-based approach to classify samples into labels. Instead it uses a distance-based approach to differentiate between samples classified under different labels. The code is available at https://tinyurl.com/DiscriminativeCHD
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