This study supports the use of MMF as a second-line immunotherapeutic in immune-mediated skin disease in dogs.

This report describes a dog that developed erythema multiforme in temporal association with administration of the sulphonamide-based anticonvulsant drug zonisamide. Similar adverse drug reactions have been associated with sulphonamide antimicrobial drugs. Caution should be exercised when prescribing this medication for dogs with known hypersensitivity to sulphonamides.

Mycoplasma infections of the middle ear may be clinically important and require targeted treatment in some cases.