Aim: To review current evidence regarding the safety of intravenous bolus magnesium sulphate for the treatment of children with acute severe asthma in the non-critical care setting. Methods: MEDLINE via Ovid, Embase and the Cochrane Library were searched for relevant articles. Results: Four hundred and eighteen articles were identified during the initial search after removal of duplicates. Eighty full-text articles were selected for review and 16 included as relevant to the clinical question. Conclusions: Current evidence suggests that bolus intravenous magnesium sulphate is safe to be administered in non-critical care settings provided that line of sight nursing and cardiorespiratory monitoring are available.
The safety of initiating enteral feeds during therapeutic hypothermia (TH) in neonates with HIE remains uncertain, and clinical practice is variable. Traditionally, enteral feeds were withheld to reduce the risk of necrotising enterocolitis (NEC) in HIE babies who may have experienced intestinal hypoperfusion. 1 However, growing evidence suggests that enteral nutrition is beneficial and promotes gut stimulation and feeding tolerance. 2 How to cite this article: de Havilland A, Hariharan G. Is enteral feeding safe during therapeutic hypothermia in neonates with hypoxic-ischaemic encephalopathy? Acta Paediatr.
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