An evaluation of the efficacy of different treatment trials in controlling Pseudomonas aeruginosa infection in quail chicks was done. Two probiotics (Lactobacilli and active dry yeast) and two fluoroquinolone antibiotics (Ciprofloxacin & ofloxacin) were used. Four-daysold quail chicks were infected orally with 0.2ml containing 3 x 108 CFU/ml of Pseudomonas aeruginsa strain which proved to be highly pathogenic for quails and sensitive to both antibiotics mentioned above. After three days, infected quails were sorted out into treated and control groups. The fluoroquinolone treated groups were given either of the antibiotics in the drinking water at a dose level of 10mg/kg BW every 12 h for five successive days, while the probiotic treated groups received either and both of the probiotics at a dose level of 0.5gm/liter daily till the end of the experiment. The results revealed that fluoroquinolones were highly effective in destroying the infectious agent. on the other hand, the general health condition and body functions were negatively affected. Histopathological changes in fluoroquinolone and probiotic treated groups were similar. Bacteriologically, the probiotics failed to remove pseudomonas from the infected internal organs. Probiotics proved to be effective in reducing mortalities, severity of infection, enhancement of liver and kidney functions up to almost normal values and improving quail immunity. Probiotics resulted in improvement of the haematological and biochemical parameters as well as total serum proteins and serum globulins. Dual administration of the lactobacilli and saccharomyces justified their synergistic probiotics effect against quail chick pseudomoniasis.Abbreviations: ALT= alanine aminotransferase; AP= alkaline phosphatase; AST= aspartate amintransferase; B= basophils; CFU= colony forming unit CFU/ml = colony forming unit per millilitre; Cipro.= ciprofloxacin; E= eosinophils; gm/ Liter = gram per liter; H= heterophils; Hb concentration = haemoglobin concentration; Hb%= haemoglobin percentage; L= lymphocytes; Lact.=lactobacillus; L. acidophilus= lactobacillus acidophilus; L. brevis= lactobacillus brevis; L. planterum= lactobacillus planterum; M= monocytes; MIC= minimum inhibitory concentration; Of= ofloxacin; PCV= packed cell volume; pH= hydrogen ion concentration; Ps= pseudomonas aeruginosa; R= resistant; TLC= total leucocytic count; T. lymphocytes = thymus dependent lymphocytes; Y= active dry yeast.
revealed a picture of hemorrhagic septicemia with enteritis. Bacteriological Examination revealed isolation of 42 isolates from 154 samples with a percentage of 27.3%. The serotyping of the isolated strains revealed that they belong to serotypes 5: A, 8: A, 9: A and 2: D while 12 isolated strains were untyped. All the isolated strains were highly pathogenic for mice and chickens. The antibiogram test revealed that highly sensitive to ciprofloxacin, trimethoprim, colistin sulphate and doxycycline and resistant for penicillin, lincomycin. The pathological changes in different internal organs revealed highly pathological changes. It could be concluded that Pasteurella multocida is highly pathogenic for ostriches and cause severe losses in ostrich farms and found that the rate of isolation of Pasterulla multocida is very high in most bacterial agents. Therefore biosecurity measures must be completely used to minimize the predisposing factors with strict hygienic measures at the farm slaughter house and back yard of ostrich farms.
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